Product image of Glucagen Hypokit (Glucagon) supplied by GNH India

Glucagen Hypokit

Active Ingredient:
Glucagon
Origin:
EU

Glucagen Hypokit (Glucagon)

Glucagen Hypokit is a prescription glucagon product supplied in a ready‑to‑use kit for intramuscular or subcutaneous injection. The kit contains the active ingredient glucagon, which is used to rapidly increase blood glucose levels in patients experiencing severe hypoglycemia. It is marketed in the European Union and is classified under the glucagon drug class for emergency hypoglycemia treatment.

Manufacturer / TM Owner

Novo Nordisk A/S

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Indications & Clinical Uses

Glucagen Hypokit is indicated for the rapid treatment of severe hypoglycemia when oral glucose administration is not feasible. It is commonly used in emergency situations for patients with diabetes who have lost consciousness or are unable to swallow. The kit provides a convenient, pre‑measured dose for immediate administration.

  • Emergency treatment of severe hypoglycemia in adults and children
  • Use when oral carbohydrate intake is impossible or ineffective
  • Administration by trained caregivers, healthcare professionals, or first responders
  • Suitable for intramuscular or subcutaneous injection in a crisis setting
  • Provides a rapid rise in blood glucose to restore normal levels

Side Effects

Glucagen Hypokit may cause a range of side effects, most of which are mild and transient. Serious adverse reactions are uncommon but require prompt medical attention.

Common

  • Nausea or vomiting
  • Injection site pain, redness, or swelling
  • Headache
  • Dizziness or light‑headedness
  • Transient hyperglycemia (elevated blood sugar)
  • Flushing or warmth sensation

Serious

  • Severe allergic reaction (anaphylaxis) with rash, itching, swelling, or difficulty breathing
  • Persistent vomiting leading to dehydration
  • Rapid heart rate (tachycardia) or irregular heartbeat
  • Severe hypoglycemia recurrence after initial treatment

Precautions & Warnings

Before using Glucagen Hypokit, certain precautions should be considered to ensure safe and effective treatment. Patients and caregivers should be aware of the following:

  • Verify the product's expiration date and inspect for discoloration before administration
  • Ensure proper injection technique to avoid intravascular delivery
  • Use only when severe hypoglycemia is confirmed and oral glucose is not an option
  • Monitor blood glucose levels after administration to assess response
  • Seek immediate medical assistance if symptoms do not improve within 15 minutes
  • Store at controlled room temperature, protected from light and moisture
  • Do not reuse the needle or syringe provided in the kit

Avoid Interactions

Glucagen Hypokit may interact with other medications or substances that affect glucose metabolism. Awareness of these interactions helps prevent adverse outcomes.

Avoid

  • Beta‑blockers, which can mask typical hypoglycemia symptoms
  • Long‑acting insulin or sulfonylureas taken shortly before glucagon administration
  • Medications that cause severe hyperglycemia, such as high‑dose corticosteroids

Use with caution

  • Oral hypoglycemic agents (e.g., metformin) that may influence glucose rebound
  • Alcohol, which can potentiate hypoglycemia and affect glucagon efficacy
  • Other hormonal agents that alter glucose homeostasis (e.g., growth hormone)

Frequently Asked Questions

Glucagen Hypokit is a ready‑to‑use glucagon kit for intramuscular or subcutaneous injection. Glucagon stimulates the liver to break down glycogen and produce glucose, rapidly raising blood sugar levels during severe hypoglycemia.

It should be used when a person with diabetes experiences severe hypoglycemia and cannot safely consume oral glucose, such as when they are unconscious, seizing, or unable to swallow.

Yes, trained caregivers, family members, or friends can administer the kit after receiving proper instruction on injection technique and dosage.

Common side effects include nausea, vomiting, injection site pain or redness, headache, dizziness, transient hyperglycemia, and a feeling of warmth.

Signs of a severe allergic reaction (rash, swelling, difficulty breathing), persistent vomiting, rapid or irregular heartbeat, or worsening hypoglycemia after treatment should prompt urgent medical care.

Store the kit at controlled room temperature, away from direct light and moisture, and keep it out of reach of children. Do not use the product past its expiration date.

The pregnancy safety category for glucagon is unknown. It should be used only if the potential benefit justifies the potential risk to the fetus, and under medical supervision.

Medications such as beta‑blockers can mask hypoglycemia symptoms, and long‑acting insulin or sulfonylureas may influence glucose levels after glucagon administration. Discuss all medications with a healthcare provider.

If blood glucose does not rise within 15 minutes, a second dose may be administered if available, and emergency medical services should be contacted immediately.

Yes, Glucagen Hypokit is a prescription‑only medication and must be prescribed by a qualified healthcare professional.

Glucagen Hypokit is indicated for use in both adults and children with severe hypoglycemia, provided the appropriate dose is administered as directed by a healthcare professional.

The kit is designed for intramuscular or subcutaneous injection, depending on the clinical situation and the injector’s training.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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