Gluconat De Calciu B.Braun Melsungen (Calcium Gluconate)

Gluconat De Calciu B.Braun Melsungen is indicated for several clinical situations where calcium supplementation is required.

• Treatment of hypocalcemia caused by surgery, trauma, or endocrine disorders.
• Management of calcium deficiency in patients with malabsorption or dietary insufficiency.
• Cardiac membrane stabilization in hyperkalemia emergencies.
• Peri‑operative calcium supplementation to support neuromuscular function.
• Adjunct therapy in certain cases of osteomalacia or rickets under medical supervision.

Side effects of calcium gluconate injection can range from mild to severe, depending on patient factors and administration technique.

Common

• Local pain, erythema, or swelling at the injection site.
• Nausea or mild vomiting.
• Transient flushing or warmth sensation.
• Mild hypercalcemia manifested as constipation or mild fatigue.

Serious

• Severe hypercalcemia leading to cardiac arrhythmias.
• Hypotension or bradycardia during rapid IV infusion.
• Tissue necrosis or ulceration from extravasation.
• Anaphylactic or severe allergic reactions.
• Cardiac arrest in extreme electrolyte imbalance.

Before administering Gluconat De Calciu B.Braun Melsungen, several safety considerations should be observed.

• Verify serum calcium levels and correct any underlying electrolyte imbalance.
• Monitor cardiac rhythm and blood pressure during rapid IV infusion.
• Avoid administration to patients with known hypercalcemia or severe renal impairment.
• Use caution in pregnant or breastfeeding women; safety data are limited.
• Ensure proper IV/IM technique to prevent extravasation and tissue injury.
• Adjust dose in patients receiving other calcium‑containing medications.

Calcium gluconate may interact with various drugs, influencing their efficacy or safety.

Avoid

• Simultaneous administration of calcium‑containing antacids or supplements that may cause hypercalcemia.
• Concurrent use of bisphosphonates, which can bind calcium and reduce absorption.
• High‑dose loop diuretics that increase calcium excretion.

Use with caution

• Digoxin or quinidine, as calcium may affect cardiac conduction.
• ACE inhibitors or thiazide diuretics, which can alter calcium balance.
• Other electrolyte solutions (magnesium, potassium) that may require monitoring.
• Blood thinners, as calcium can influence clotting factors.