Product image of Glucose 20% Labesfal (Glucose) supplied by GNH India

Glucose 20% Labesfal

Active Ingredient:
Glucose
Origin:
EU

Glucose 20% Labesfal (Glucose)

Glucose 20% Labesfal is an intravenous solution containing 20% w/v glucose as the active ingredient. It is supplied in a sterile liquid form intended for infusion into the bloodstream. The product is manufactured for the European Union market and is used as a source of carbohydrate energy in clinical settings where rapid glucose delivery is required.

Manufacturer / TM Owner

Labesfal Laboratorios Almiro, S.A.

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Indications & Clinical Uses

Glucose 20% Labesfal is employed in various medical situations where a quick increase in blood glucose is needed. It is commonly used for:

  • Treating hypoglycemia in patients unable to take oral glucose.
  • Providing caloric support during surgery or intensive care.
  • Serving as a carrier for other intravenous medications.
  • Maintaining fluid and electrolyte balance in patients receiving parenteral nutrition.
  • Supporting patients with metabolic disorders that require controlled glucose administration.

Side Effects

Glucose 20% Labesfal may cause a range of reactions, most of which are related to its osmolarity and carbohydrate content.

Common

  • Mild hyperglycemia (elevated blood sugar levels).
  • Local irritation at the infusion site.
  • Nausea or vomiting.
  • Headache.
  • Transient electrolyte shifts, such as low potassium.

Serious

  • Severe hyperglycemia leading to osmotic diuresis.
  • Hyperosmolar hyperglycemic state (HHS) in susceptible individuals.
  • Allergic reaction or anaphylaxis (rare).
  • Fluid overload, especially in patients with cardiac or renal impairment.

Precautions & Warnings

When using Glucose 20% Labesfal, clinicians should consider several safety measures. Important precautions include:

  • Assessing baseline blood glucose and electrolyte levels before infusion.
  • Monitoring blood glucose frequently during and after administration.
  • Adjusting infusion rates in patients with diabetes, renal insufficiency, or heart failure.
  • Avoiding rapid infusion in neonates and infants due to risk of hyperosmolar injury.
  • Ensuring proper aseptic technique to prevent contamination.
  • Verifying compatibility with other IV solutions or medications before co‑administration.

Avoid Interactions

Glucose 20% Labesfal can interact with other agents, influencing its safety and efficacy. Interaction considerations are:

Avoid

  • Co‑administration with high‑dose insulin without close glucose monitoring.
  • Simultaneous infusion of other hyperosmolar solutions that may exacerbate fluid overload.

Use with caution

  • Concurrent use of diuretics, which may affect electrolyte balance.
  • Medications that alter glucose metabolism, such as corticosteroids or beta‑agonists.
  • Intravenous potassium supplements, due to risk of shifting potassium levels.
  • Drugs that require a specific pH environment, as glucose solutions can affect pH.

Frequently Asked Questions

Glucose 20% Labesfal is a sterile intravenous solution containing 20% glucose. It is administered through a vein using an infusion set, allowing rapid delivery of carbohydrate energy directly into the bloodstream.

It is commonly used to treat acute hypoglycemia, provide caloric support during surgery or intensive care, serve as a carrier for other IV drugs, and maintain fluid balance in patients receiving parenteral nutrition.

Common side effects include mild hyperglycemia, local irritation at the infusion site, nausea, headache, and transient electrolyte shifts such as low potassium.

Serious reactions may include severe hyperglycemia, hyperosmolar hyperglycemic state, rare allergic reactions or anaphylaxis, and fluid overload, especially in patients with heart or kidney disease.

Blood glucose should be measured before starting the infusion, then frequently (e.g., every 30–60 minutes) during administration and after the infusion to detect any rapid changes.

Yes, patients with diabetes require careful monitoring of blood glucose and may need adjustments to insulin therapy to avoid excessive hyperglycemia.

Compatibility should be verified before mixing. Some drugs may be incompatible due to differences in pH or osmolarity, and co‑administration can affect the stability of both solutions.

Avoid concurrent high‑dose insulin without monitoring, and use caution with diuretics, corticosteroids, beta‑agonists, potassium supplements, and medications that require a specific pH environment.

Infusion rates should be carefully controlled in neonates and infants to prevent hyperosmolar injury; pediatric dosing guidelines must be followed.

The infusion should be stopped immediately, and appropriate emergency measures, such as administration of antihistamines or epinephrine, should be taken according to clinical protocols.

The high osmolarity can cause vein irritation and fluid shifts; therefore, infusion should be performed through a large vein and at a controlled rate, especially in patients at risk for fluid overload.

Glucose 20% Labesfal is approved for use within the European Union market.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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