Product image of Glucose B. Braun (Glucose Monohydrate) supplied by GNH India

Glucose B. Braun

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucose B. Braun (Glucose Monohydrate)

Glucose B. Braun is a sterile solution for injection that contains glucose monohydrate as its active ingredient. It is supplied as an intravenous carbohydrate solution without a listed strength, intended for use in parenteral nutrition, fluid and electrolyte replacement, and treatment of hypoglycemia. The product is marketed in the European Union and is available by prescription only.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Glucose B. Braun is employed in clinical settings where rapid delivery of carbohydrate energy is required. It supports patients who cannot receive nutrition orally or enterally.

  • Management of hypoglycemia in acute care environments.
  • Component of parenteral nutrition regimens for adult and pediatric patients.
  • Fluid and electrolyte replacement during surgery or trauma.
  • Intra‑operative glucose supplementation to maintain blood sugar levels.
  • Post‑operative support for patients unable to resume oral intake.
  • Neonatal and infant nutrition when enteral feeding is not feasible.

Side Effects

Glucose B. Braun may cause a range of adverse reactions, most of which are mild and transient. Serious events are less common but require immediate medical attention.

Common

  • Hyperglycemia or elevated blood glucose levels.
  • Local irritation at the infusion site.
  • Mild nausea or vomiting.
  • Headache.
  • Transient hypotension during rapid infusion.

Serious

  • Severe hyperglycemia leading to diabetic ketoacidosis.
  • Allergic reaction or anaphylaxis.
  • Electrolyte imbalance, especially hypernatremia.
  • Fluid overload with pulmonary edema.
  • Metabolic acidosis in susceptible patients.

Precautions & Warnings

Healthcare professionals should assess patient-specific factors before administering Glucose B. Braun. Proper monitoring can reduce the risk of complications.

  • Verify blood glucose levels prior to infusion and adjust rate accordingly.
  • Use caution in patients with diabetes mellitus or impaired glucose tolerance.
  • Monitor fluid balance to avoid overload, especially in heart or renal failure.
  • Assess electrolyte status, particularly sodium and potassium, before and during therapy.
  • Avoid rapid infusion rates that may cause hypotension.
  • Pregnant or lactating patients should be evaluated on a case‑by‑case basis.
  • Store the solution according to manufacturer instructions to maintain sterility.

Avoid Interactions

Glucose B. Braun can interact with other medications or solutions administered intravenously. Some combinations should be avoided, while others require careful monitoring.

Avoid

  • Concurrent infusion of high‑concentration potassium solutions, which may precipitate.
  • Co‑administration with insulin without appropriate glucose monitoring.
  • Use with medications that contain dextrose or other sugars, which could cause hyperglycemia.

Use with caution

  • Loop diuretics, as they may exacerbate electrolyte shifts.
  • Beta‑blockers, which can mask signs of hypoglycemia.
  • Corticosteroids, which can increase glucose production.
  • Total parenteral nutrition admixtures, requiring compatibility testing.
  • Vasopressors, where rapid changes in osmolarity could affect hemodynamics.

Frequently Asked Questions

Glucose B. Braun is a sterile intravenous solution that contains glucose monohydrate as its sole active ingredient, providing a source of carbohydrate energy for patients who cannot eat or drink.

It is commonly used to treat acute hypoglycemia, as part of parenteral nutrition regimens, and for fluid and electrolyte replacement during surgery, trauma, or when oral intake is not possible.

The product is administered intravenously by a qualified healthcare professional, with the infusion rate adjusted based on the patient’s blood glucose level, fluid status, and clinical condition.

The solution should be stored at controlled room temperature, protected from light, and kept in its original packaging until use to maintain sterility and potency.

Yes, it can be used in pediatric and neonatal patients when parenteral nutrition or glucose supplementation is required, but dosing and infusion rates must be individualized by a pediatric specialist.

Blood glucose levels, electrolyte concentrations, and fluid balance should be regularly monitored to detect hyperglycemia, electrolyte disturbances, or fluid overload.

The solution should be avoided in patients with known hypersensitivity to glucose monohydrate or in those where rapid glucose infusion could exacerbate existing metabolic disorders without proper monitoring.

Common side effects include transient hyperglycemia, mild nausea, headache, local infusion site irritation, and temporary low blood pressure if infused too quickly.

Serious reactions include severe hyperglycemia leading to ketoacidosis, allergic reactions such as anaphylaxis, electrolyte imbalances, fluid overload with pulmonary edema, and metabolic acidosis.

When insulin is administered concurrently, glucose levels must be closely monitored to avoid hypoglycemia or excessive hyperglycemia, and infusion rates may need adjustment.

The pregnancy safety category is listed as unknown; therefore, it should be used only if the potential benefit justifies the potential risk to the fetus, under medical supervision.

The infusion should be stopped immediately, the patient assessed, and appropriate medical treatment initiated, which may include antihistamines, corticosteroids, or emergency measures for anaphylaxis.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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