Glucose B.Braun Melsungen (Glucose Monohydrate)

Glucose B.Braun Melsungen is indicated for several clinical situations where rapid elevation of plasma glucose or fluid replacement is required.

• Treatment of hypoglycemia in patients unable to take oral glucose.
• Fluid and electrolyte replacement during dehydration or surgery.
• Component of parenteral nutrition regimens to provide an energy source.
• Support for patients receiving intravenous medications that may lower blood glucose.
• Management of electrolyte imbalances when combined with appropriate salts.

Intravenous administration of glucose solution may be associated with a range of adverse reactions, most of which are mild and transient.

Common

• Mild hyperglycemia or transient rise in blood glucose.
• Local irritation or pain at the injection site.
• Nausea or mild vomiting.
• Headache or dizziness.

Serious

• Severe hyperglycemia leading to osmotic diuresis.
• Electrolyte disturbances such as hyponatremia.
• Allergic reactions including rash, urticaria, or anaphylaxis.
• Volume overload in patients with cardiac or renal impairment.

Glucose B.Braun Melsungen should be used with caution in specific patient populations and clinical conditions.

• Assess blood glucose levels before and during infusion to avoid hyperglycemia.
• Adjust infusion rate in patients with renal or cardiac failure to prevent fluid overload.
• Use reduced concentrations in neonates and pediatric patients.
• Avoid use in patients with known hypersensitivity to glucose solutions.
• Monitor electrolyte balance, especially sodium and potassium, during prolonged therapy.
• Consider compatibility with other intravenous drugs before co‑administration.

Glucose solutions can interact with other intravenous agents, affecting their efficacy or safety.

Avoid

• Co‑administration with high‑dose insulin infusions without appropriate glucose monitoring.
• Simultaneous infusion of potassium chloride in concentrations that may precipitate.
• Mixing with calcium‑containing solutions that can cause precipitation.

Use with caution

• Concurrent use of diuretics that may alter fluid and electrolyte status.
• Administration alongside beta‑blockers, which can mask signs of hypoglycemia.
• Use with other hyperosmolar solutions, requiring careful monitoring of osmolarity.