Product image of Glucose Com Cloreto De Sodio Basi (Sodium Chloride, Glucose) supplied by GNH India

Glucose Com Cloreto De Sodio Basi

Active Ingredient:
Sodium Chloride, Glucose
Origin:
EU

Glucose Com Cloreto De Sodio Basi (Sodium Chloride, Glucose)

Glucose Com Cloreto De Sodio Basi is a sterile aqueous solution for injection that combines sodium chloride and glucose as its active ingredients. The product is supplied in a ready‑to‑use liquid form intended for intravenous administration. It is manufactured for the European market and conforms to EU pharmaceutical standards, providing an isotonic carrier that can be used in various clinical settings where fluid and electrolyte replacement is required.

Manufacturer / TM Owner

Laboratórios Basi – Indústria Farmacêutica, S.A.

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Indications & Clinical Uses

Glucose Com Cloreto De Sodio Basi is employed in clinical practice primarily as an intravenous fluid to support patients who need volume expansion and electrolyte balance.

  • Replenishment of extracellular fluid volume in dehydration or blood loss.
  • Provision of sodium and chloride ions to maintain plasma osmolality.
  • Supply of glucose as an immediate energy substrate during peri‑operative care.
  • Dilution and compatible administration of other intravenous medications.
  • Support for patients receiving parenteral nutrition or undergoing dialysis.
  • Temporary correction of mild hyponatremia when rapid sodium increase is not required.

Side Effects

The safety profile of Glucose Com Cloreto De Sodio Basi reflects the typical reactions observed with isotonic sodium chloride and glucose solutions administered intravenously.

Common

  • Mild pain or irritation at the injection site.
  • Transient increase in blood glucose levels.
  • Slight elevation of serum sodium concentration.
  • Temporary feeling of warmth or flushing during infusion.
  • Minor electrolyte shifts that resolve without intervention.
  • Slight increase in urine output during and shortly after infusion.

Serious

  • Hypernatremia resulting from excessive sodium load.
  • Hyperglycemia in patients with impaired glucose tolerance.
  • Allergic or anaphylactic reaction to the solution components.
  • Fluid overload in patients with compromised cardiac function.
  • Metabolic acidosis if administered in large volumes rapidly.

Precautions & Warnings

When using Glucose Com Cloreto De Sodio Basi, clinicians should observe specific precautions to minimize risks and ensure appropriate patient selection.

  • Assess baseline serum electrolytes and glucose before administration.
  • Adjust infusion rate in patients with cardiac or renal impairment.
  • Avoid use in individuals with known hypersensitivity to sodium chloride or glucose.
  • Monitor fluid balance to prevent overload in susceptible patients.
  • Use compatible IV sets and avoid mixing with drugs that may precipitate.
  • Document infusion volume and rate in the patient’s medical record.
  • Consider alternative isotonic solutions if the patient requires specific electrolyte composition.

Avoid Interactions

Glucose Com Cloreto De Sodio Basi may interact with other intravenous agents; awareness of compatible and incompatible combinations helps maintain solution stability and patient safety.

Avoid

  • Do not mix with calcium-containing solutions, as precipitation of calcium chloride may occur.
  • Avoid concurrent infusion with high‑concentration dextrose solutions that could cause hyperosmolarity.

Use with caution

  • Co‑administration with potassium chloride requires careful monitoring of serum potassium levels.
  • Concurrent use with diuretics may amplify electrolyte shifts; monitor electrolytes closely.
  • When combined with blood products, ensure compatible infusion rates to prevent hemolysis.
  • Use cautiously with insulin therapy, as glucose load may affect glycemic control.

Frequently Asked Questions

It is used as an intravenous solution to provide fluid volume, sodium chloride, and glucose for patients needing hydration, electrolyte balance, or energy support.

The product may be administered to children under medical supervision, with dosing and infusion rates adjusted according to age, weight, and clinical condition.

Sodium chloride contributes to maintaining isotonicity, helping to keep plasma osmolality within normal ranges during infusion.

Compatibility depends on the specific drug; it is generally compatible with many medications, but should not be mixed with calcium‑containing solutions or high‑concentration dextrose products.

Clinicians should monitor vital signs, serum electrolytes, blood glucose, fluid balance, and any signs of adverse reactions throughout the infusion.

It can be used with caution; infusion rates may need adjustment and electrolyte levels should be closely monitored in renal impairment.

Symptoms may include thirst, confusion, muscle twitching, and in severe cases, seizures or coma; laboratory testing confirms elevated serum sodium.

Glucose can raise blood sugar levels; diabetic patients should have their glucose monitored and may require insulin adjustments during infusion.

Allergic reactions are rare but possible; signs include rash, itching, swelling, or anaphylaxis, which require immediate medical attention.

The infusion volume, rate, start and stop times, patient response, and any observed adverse events should be recorded in the medical record.

Glucose Com Cloreto De Sodio Basi is a sterile, preservative‑free solution intended for single‑use administration.

It should be stored at controlled room temperature, protected from light, and used before the expiration date indicated on the packaging.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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