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Glucose Fresenius

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucose Fresenius (Glucose Monohydrate)

Glucose Fresenius is an intravenous solution for injection that contains glucose monohydrate as its active ingredient; the product is supplied in a standard concentration (strength not specified) and is marketed in the European Union as a prescription‑only nutritional supplement used to provide carbohydrate calories and raise blood glucose levels. It is administered by healthcare professionals under controlled conditions and is classified as an excipient/solvent within the ATC group A12BA01.

Manufacturer / TM Owner

Fresenius Kabi Polska Sp. Z O.O.

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Indications & Clinical Uses

Glucose Fresenius is indicated for several clinical situations where rapid carbohydrate delivery or fluid replacement is required.

  • Treatment of acute hypoglycemia in emergency settings.
  • Component of parenteral nutrition regimens for patients unable to receive enteral feeding.
  • Support of fluid and electrolyte balance during peri‑operative care.
  • Provision of caloric substrate in critical‑care or pediatric patients.
  • Management of electrolyte disturbances associated with glucose infusion.

Side Effects

When administered intravenously, Glucose Fresenius may be associated with a range of observed effects, most of which are related to its carbohydrate load and infusion characteristics.

Common

  • Transient hyperglycemia or elevated blood glucose readings.
  • Local irritation or phlebitis at the infusion site.
  • Mild nausea or vomiting.
  • Electrolyte shifts such as mild hypokalemia.

Serious

  • Severe hyperglycemia leading to osmotic diuresis or ketoacidosis.
  • Anaphylactic or severe allergic reaction.
  • Fluid overload causing pulmonary edema or cardiac strain.

Precautions & Warnings

Clinicians should observe several precautions before and during the use of Glucose Fresenius to minimize risks.

  • Verify blood glucose level and adjust infusion rate in diabetic or hyperglycemic patients.
  • Assess fluid status to avoid overload in patients with heart or renal failure.
  • Monitor electrolytes, especially potassium and sodium, during prolonged infusion.
  • Use aseptic technique and inspect solution for particulates before administration.
  • Consider pregnancy status; safety data are limited.
  • Store according to manufacturer guidelines to maintain solution stability.

Avoid Interactions

Glucose Fresenius can interact with other medications or solutions administered intravenously; awareness of these interactions helps ensure safe therapy.

Avoid

  • Co‑administration with high‑dose insulin or other potent hypoglycemic agents without glucose monitoring.
  • Simultaneous infusion of potassium‑containing solutions that may precipitate with calcium.

Use with caution

  • Concurrent use of diuretics that affect fluid and electrolyte balance.
  • Beta‑blockers or catecholamines that may mask hypoglycemia symptoms.
  • Corticosteroids that increase glucose production.
  • Other carbohydrate‑containing IV fluids that could raise total caloric load.

Frequently Asked Questions

Glucose Fresenius provides a rapid source of carbohydrate calories and raises blood glucose levels when given intravenously, making it useful for treating hypoglycemia and supporting parenteral nutrition.

It is commonly used for acute hypoglycemia, as part of parenteral nutrition, during peri‑operative fluid management, in critical‑care or pediatric patients needing caloric support, and for correcting electrolyte imbalances linked to glucose infusion.

The product is supplied as a sterile solution for injection and is administered intravenously by a qualified healthcare professional, usually via a controlled infusion pump.

Blood glucose levels, fluid balance, and electrolytes (especially potassium and sodium) should be regularly checked, and the infusion site inspected for signs of phlebitis or irritation.

Yes, but the infusion rate should be individualized and closely monitored to avoid excessive hyperglycemia, and adjustments to the patient’s existing diabetes regimen may be required.

Common reactions include transient hyperglycemia, mild nausea, local irritation or phlebitis at the infusion site, and small shifts in electrolyte levels such as mild hypokalemia.

The solution should be stored at the temperature recommended by the manufacturer, protected from light, and kept in its original sealed container until it is prepared for infusion.

It is generally compatible with most isotonic crystalloids, but compatibility should be confirmed when mixing with calcium‑containing or high‑potassium solutions to avoid precipitation.

Pregnancy safety data are limited; the drug should be used only if clearly needed and after evaluating the risk‑benefit ratio by the treating physician.

Glucose Fresenius is delivered directly into the bloodstream, providing immediate elevation of blood glucose, whereas oral tablets must be absorbed through the gastrointestinal tract, resulting in a slower onset.

The infusion should be slowed or stopped, blood glucose re‑checked, and appropriate medical interventions such as insulin administration may be considered under physician guidance.

Used containers should be disposed of according to local regulations for medical waste, ensuring that any residual solution is safely neutralized or discarded.

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GNH India Pharmaceuticals Limited

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Last updated:

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