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Glucose Fresenius

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucose Fresenius (Glucose Monohydrate)

Glucose Fresenius is an intravenous solution for injection that contains the active ingredient glucose monohydrate. The product’s strength is not specified in the available data, and it is supplied as a sterile solution intended for parenteral administration. As an excipient and solvent, it provides carbohydrate energy and fluid volume when infused. It is marketed within the European Union and is classified under ATC code B05BA01 for parenteral nutrition and fluid replacement.

Manufacturer / TM Owner

Fresenius Kabi Polska Sp. Z O.O.

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Indications & Clinical Uses

Glucose Fresenius is used in clinical settings to address conditions that require rapid carbohydrate supplementation or fluid replacement.

  • Treatment of hypoglycemia when oral glucose is not feasible.
  • Component of parenteral nutrition regimens for patients unable to receive enteral feeding.
  • Fluid replacement in patients with dehydration or electrolyte imbalance.
  • Support during surgical procedures to maintain blood glucose levels.
  • Adjunct therapy in critical care to provide an energy substrate.

Side Effects

Intravenous administration of glucose solutions may be associated with a range of adverse effects, most of which are related to the osmolarity and rapid infusion of carbohydrate.

Common

  • Transient hyperglycemia.
  • Local irritation or pain at the infusion site.
  • Nausea or mild vomiting.
  • Electrolyte shifts such as mild hyponatremia.

Serious

  • Severe hyperglycemia leading to osmotic diuresis.
  • Fluid overload and pulmonary edema.
  • Hyperosmolar hyperglycemic state (HHS) in susceptible patients.
  • Allergic or anaphylactic reaction to the solution.

Precautions & Warnings

Before administering Glucose Fresenius, clinicians should evaluate patient-specific factors and monitor for potential complications.

  • Assess baseline blood glucose and adjust infusion rate accordingly.
  • Use caution in patients with renal or cardiac failure due to risk of fluid overload.
  • Avoid rapid infusion in neonates and infants to prevent hyperglycemia.
  • Monitor electrolytes, especially sodium and potassium, during therapy.
  • Ensure sterility of the solution and proper storage conditions.
  • Consider contraindications such as known hypersensitivity to glucose solutions.

Avoid Interactions

Glucose Fresenius may interact with other medications or clinical conditions, influencing its safety and efficacy.

Avoid

  • Co-administration with insulin bolus doses without adjusting the insulin regimen.
  • Simultaneous infusion of high‑osmolarity solutions that may exacerbate hyperglycemia.
  • Use in patients receiving diuretics that predispose to electrolyte disturbances without monitoring.

Use with caution

  • Concurrent use of beta‑blockers, which can mask signs of hypoglycemia.
  • Administration alongside corticosteroids that increase glucose production.
  • Patients on total parenteral nutrition formulas; adjust total carbohydrate load.

Frequently Asked Questions

Glucose Fresenius is a sterile intravenous solution for injection that contains glucose monohydrate as its active ingredient.

The product is administered intravenously, typically by slow infusion into a vein under aseptic conditions.

It is indicated for the treatment of hypoglycemia, as a component of parenteral nutrition, and for fluid replacement in patients with dehydration or electrolyte imbalance.

Common side effects include transient hyperglycemia, local irritation at the infusion site, mild nausea or vomiting, and mild electrolyte shifts such as hyponatremia.

Serious reactions may present as severe hyperglycemia, fluid overload with pulmonary edema, hyperosmolar hyperglycemic state, or an allergic/anaphylactic response.

Precautions include checking baseline blood glucose, assessing renal and cardiac function, avoiding rapid infusion in neonates, monitoring electrolytes, and confirming solution sterility.

Blood glucose levels should be measured before initiation and then regularly throughout the infusion to adjust the rate as needed.

It can be used with insulin, but insulin doses may need adjustment to avoid excessive hyperglycemia or hypoglycemia.

Interactions to consider include concurrent insulin, high‑osmolarity solutions, diuretics affecting electrolytes, beta‑blockers that mask hypoglycemia, and corticosteroids that raise glucose levels.

The solution should be stored according to the manufacturer’s instructions, typically at controlled room temperature, protected from light, and used with aseptic technique.

It may be used in pediatric patients, but infusion rates and concentrations should be carefully adjusted and monitored.

The product is classified under ATC code B05BA01, which corresponds to solutions providing carbohydrate energy and fluid volume.

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GNH India Pharmaceuticals Limited

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Last updated:

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