Glucose Sterop (Glucose Monohydrate)

Glucose Sterop is indicated for several clinical situations where rapid glucose delivery or plasma volume expansion is required.

• Treatment of hypoglycemia when oral glucose is not feasible.
• Fluid and electrolyte replacement in patients needing isotonic solutions.
• Parenteral nutrition as a carbohydrate source in total or supplemental feeding.
• Intraoperative glucose supplementation to maintain blood glucose levels during surgery.
• Support of hemodynamic stability in trauma or burn patients through osmotic volume expansion.

Adverse reactions to Glucose Sterop are generally related to its osmotic and metabolic properties.

Common

• Mild hyperglycemia, especially with large-volume infusions.
• Local irritation or pain at the injection site.
• Nausea or vomiting.
• Electrolyte disturbances such as hyponatremia.
• Transient increase in serum osmolality.

Serious

• Severe hyperglycemia leading to osmotic diuresis.
• Fluid overload with pulmonary edema.
• Allergic reactions ranging from urticaria to anaphylaxis.
• Hyperosmolar hyperglycemic state in susceptible patients.
• Metabolic acidosis in cases of massive infusion.

When prescribing Glucose Sterop, clinicians should consider several safety factors to minimize risk.

• Assess baseline blood glucose and adjust infusion rate accordingly.
• Monitor serum electrolytes, particularly sodium and potassium, during therapy.
• Use caution in patients with renal or cardiac insufficiency due to risk of fluid overload.
• Avoid rapid infusion in neonates and infants because of immature metabolic capacity.
• Evaluate for a history of hypersensitivity to glucose solutions before administration.
• Consider alternative carbohydrate sources in patients with uncontrolled diabetes.
• Ensure proper aseptic technique to prevent contamination.

Glucose Sterop may interact with other agents that affect glucose metabolism or fluid balance.

Avoid

• Concurrent high-dose insulin therapy without close glucose monitoring.
• Other hypertonic carbohydrate solutions that could exacerbate hyperglycemia.
• Sodium-containing fluids in excess, increasing risk of hypernatremia.

Use with caution

• Diuretics, which may alter electrolyte status during volume expansion.
• Corticosteroids, which can raise blood glucose levels.
• Beta‑adrenergic agonists that may affect glucose utilization.
• Renal replacement therapies that modify fluid and electrolyte balance.