Product image of Glucosio Con Sodio Cloruro I Monico (Sodium Chloride, Glucose Monohydrate) supplied by GNH India

Glucosio Con Sodio Cloruro I Monico

Active Ingredient:
Sodium Chloride, Glucose Monohydrate
Origin:
EU

Glucosio Con Sodio Cloruro I Monico (Sodium Chloride, Glucose Monohydrate)

Glucosio Con Sodio Cloruro I Monico is an injectable solution that contains sodium chloride and glucose monohydrate as its active ingredients. It is supplied as a sterile intravenous fluid without a specified strength, intended for use in clinical settings within the European Union. The product is classified as a prescription‑only IV electrolyte solution designed to help restore extracellular fluid volume and provide metabolic energy to patients.

Manufacturer / TM Owner

Monico S.P.A.

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Indications & Clinical Uses

Glucosio Con Sodio Cloruro I Monico is used in hospital and emergency settings for fluid and electrolyte management.

  • Replacement of extracellular fluid losses due to surgery, trauma, or burns.
  • Correction of hyponatremia or hypochloremia when rapid volume expansion is required.
  • Support of blood glucose levels in patients at risk of hypoglycemia.
  • Provision of an energy substrate during parenteral nutrition or peri‑operative care.
  • Maintenance of electrolyte balance during dialysis or continuous renal replacement therapy.
  • Facilitation of fluid resuscitation in patients with septic shock or severe dehydration.

Side Effects

Adverse reactions to Glucosio Con Sodio Cloruro I Monico are generally infrequent, but they may occur with any intravenous therapy and are typically related to the solution composition or infusion rate.

Common

  • Mild pain, burning, or irritation at the injection site.
  • Transient increase in serum sodium or chloride levels.
  • Temporary hyperglycemia, especially in patients receiving large volumes.
  • Slight edema or fluid overload in individuals with compromised cardiac function.
  • Local phlebitis or vein inflammation at the catheter site.

Serious

  • Severe electrolyte imbalance such as hypernatremia or hyperchloremia.
  • Anaphylactic or severe hypersensitivity reactions.
  • Pulmonary edema due to rapid infusion in susceptible patients.
  • Cardiac arrhythmias associated with rapid shifts in electrolyte concentrations.

Precautions & Warnings

When administering Glucosio Con Sodio Cloruro I Monico, clinicians should observe several precautions to minimize risks and ensure appropriate therapy.

  • Verify patient’s electrolyte status and glucose level before infusion.
  • Adjust infusion rate in patients with cardiac, renal, or hepatic impairment.
  • Use aseptic technique and inspect the solution for particulate matter or discoloration.
  • Monitor vital signs and fluid balance throughout the administration.
  • Avoid rapid bolus administration unless specifically indicated.
  • Consider compatibility with other intravenous drugs; incompatibility may cause precipitation.
  • Document the indication, dose, and any adverse observations in the medical record.

Avoid Interactions

Glucosio Con Sodio Cloruro I Monico may interact with other intravenous agents; awareness of potential incompatibilities helps maintain solution stability and patient safety.

Avoid

  • Co‑administration with calcium‑containing solutions, which can precipitate calcium chloride.
  • Mixing with alkaline drugs (e.g., sodium bicarbonate) that may cause pH shifts and precipitation.

Use with caution

  • Concurrent use of other hypertonic saline or glucose solutions, which can exacerbate electrolyte disturbances.
  • Administration alongside diuretics, especially loop diuretics, requiring close monitoring of fluid balance.
  • Use with vasopressors or inotropes, as rapid volume changes may affect hemodynamic response.
  • Concurrent administration with blood products may require separate IV lines to prevent incompatibility.

Frequently Asked Questions

It is used to replace extracellular fluid volume and provide sodium, chloride, and glucose for metabolic energy in patients needing fluid and electrolyte support.

It is commonly given after surgery, trauma, burns, during dialysis, or when patients have hyponatremia, hypochloremia, or risk of hypoglycemia.

It may be used with caution; infusion rates should be adjusted and fluid balance closely monitored to avoid overload.

No, mixing with calcium‑containing solutions should be avoided because calcium chloride can precipitate.

Vital signs, serum electrolytes, glucose levels, and overall fluid balance should be monitored throughout the infusion.

The product is supplied as a sterile, preservative‑free injection solution intended for single‑use administration.

Glucose provides an immediate source of metabolic energy and can help prevent or treat hypoglycemia during acute care.

Compatibility should be verified; some drugs may be incompatible and cause precipitation or pH changes.

Symptoms may include severe nausea, vomiting, confusion, cardiac arrhythmias, or signs of pulmonary edema and require immediate medical attention.

The product is marketed in the EU; use in other regions depends on local regulatory approval.

The infusion should be stopped immediately, and appropriate emergency measures, such as administration of antihistamines or epinephrine, should be taken.

The exact concentration is not specified in the available information; clinicians should refer to the product label for detailed composition.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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