Product image of Glucosio Monico (Glucose Monohydrate) supplied by GNH India

Glucosio Monico

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucosio Monico (Glucose Monohydrate)

Glucosio Monico is a pharmaceutical product that contains glucose monohydrate as its sole active ingredient, supplied as an intravenous solution for injection. Marketed in the European Union and available by prescription, it is formulated to deliver a sterile, isotonic glucose solution for clinical use. The preparation is used primarily in settings that require rapid provision of carbohydrate energy and fluid replacement and electrolyte balance during treatment.

Manufacturer / TM Owner

Monico S.P.A.

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Indications & Clinical Uses

Glucosio Monico is indicated for several clinical situations where rapid carbohydrate delivery and fluid support are required.

  • Treatment of hypoglycemia when oral glucose is not feasible.
  • Provision of calories in parenteral nutrition regimens.
  • Fluid replacement in patients with dehydration or electrolyte loss.
  • Support during perioperative care to maintain blood glucose levels.
  • Management of electrolyte disturbances when combined with appropriate salts.

Side Effects

Adverse reactions to Glucosio Monico are generally related to the intravenous administration of a glucose solution.

Common

  • Mild hyperglycemia
  • Local irritation at the injection site
  • Nausea or vomiting
  • Transient headache

Serious

  • Severe hyperglycemia leading to osmotic diuresis
  • Allergic reactions such as rash, urticaria, or anaphylaxis
  • Electrolyte imbalance, particularly hyponatremia
  • Volume overload in patients with cardiac or renal impairment

Precautions & Warnings

When prescribing Glucosio Monico, clinicians should consider several safety precautions to minimize risks.

  • Assess baseline blood glucose and monitor levels during infusion.
  • Adjust infusion rate in patients with diabetes or impaired glucose tolerance.
  • Use caution in individuals with renal or cardiac failure due to risk of fluid overload.
  • Verify compatibility with other intravenous solutions before mixing.
  • Avoid rapid administration in neonates and infants.
  • Review electrolyte status, especially sodium and potassium, prior to therapy.
  • Document any prior hypersensitivity to glucose solutions.

Avoid Interactions

Glucosio Monico may interact with other medications or solutions administered intravenously.

Avoid

  • Concurrent infusion of high‑concentration dextrose solutions that could cause hyperosmolarity.
  • Co‑administration with insulin bolus doses without appropriate glucose monitoring.
  • Mixing with calcium‑containing solutions that may precipitate.

Use with caution

  • Concurrent use of diuretics, which may alter fluid balance.
  • Administration alongside beta‑blockers, which can mask hypoglycemia symptoms.
  • Use with electrolyte‑replacing agents; monitor serum levels closely.
  • Combination with other carbohydrate‑containing parenterals; adjust total glucose load.

Frequently Asked Questions

Glucosio Monico is a prescription‑only intravenous solution that contains glucose monohydrate as its active ingredient. It is administered by slow infusion into a vein under medical supervision.

It is commonly used for treating hypoglycemia, providing calories in parenteral nutrition, and delivering fluid replacement in patients who cannot take oral fluids.

Use in neonates and infants should be cautious, and rapid administration is generally avoided. Pediatric dosing must be determined by a qualified healthcare professional.

Blood glucose levels should be measured before, during, and after the infusion, and fluid balance and electrolyte status should be regularly assessed.

Allergic reactions are rare but possible; signs may include rash, itching, swelling, or anaphylaxis, and immediate medical attention is required if they occur.

Glucosio Monico delivers glucose directly into the bloodstream, providing a rapid rise in blood sugar, whereas oral tablets must be absorbed through the gastrointestinal tract, which can be slower or impossible in certain patients.

Compatibility should be confirmed before mixing. It should not be combined with calcium‑containing solutions or high‑concentration dextrose solutions without proper assessment.

Symptoms may include shortness of breath, peripheral edema, elevated blood pressure, or worsening heart failure, and the infusion should be stopped if these occur.

Patients with diabetes can receive Glucosio Monico, but infusion rates must be carefully adjusted and blood glucose closely monitored to avoid hyperglycemia.

The infusion should be slowed or stopped, and insulin therapy may be considered according to the treating physician’s protocol.

The product is a sterile, isotonic glucose solution intended as a solvent; it does not contain additional active pharmacologic agents.

Prescribing information is available from the national regulatory agency in the EU member state where the product is marketed, as well as from the manufacturer’s official website.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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