Product image of Glucosio S.A.L.F. (Glucose Monohydrate) supplied by GNH India

Glucosio S.A.L.F.

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucosio S.A.L.F. (Glucose Monohydrate)

Glucosio S.A.L.F. is a sterile intravenous solution containing glucose monohydrate as the active ingredient. It is supplied as a solution for injection, intended for parenteral administration in clinical settings. The product conforms to EU pharmaceutical standards and is classified as an excipient used to provide an immediate source of carbohydrate energy. The formulation is supplied in sterile containers suitable for pharmacy use.

Manufacturer / TM Owner

S.A.L.F. Spa Laboratorio Farmacologico

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Indications & Clinical Uses

Glucosio S.A.L.F. is used as an intravenous carbohydrate source in a variety of clinical situations where rapid energy supplementation is required.

  • To provide caloric support during short‑term fasting or pre‑operative preparation.
  • As a diluent or carrier for compatible parenteral medications.
  • To correct hypoglycemia when oral intake is not feasible.
  • In fluid resuscitation protocols where glucose is needed alongside electrolytes.
  • For maintenance of blood glucose levels during total parenteral nutrition (TPN) admixtures.

Side Effects

When administered intravenously, Glucosio S.A.L.F. may be associated with a range of observed effects, most of which are related to the glucose load.

Common

  • Transient hyperglycemia that resolves with metabolic clearance.
  • Mild venous irritation at the infusion site.
  • Temporary increase in serum osmolality.
  • Nausea or mild abdominal discomfort in susceptible individuals.

Serious

  • Severe hyperglycemia leading to osmotic diuresis.
  • Electrolyte imbalance, particularly hypokalemia.
  • Allergic or anaphylactoid reaction to formulation excipients.
  • Fluid overload in patients with compromised cardiac function.

Precautions & Warnings

Healthcare professionals should observe specific precautions when selecting Glucosio S.A.L.F. for intravenous therapy to minimize risks.

  • Verify patient’s baseline blood glucose and adjust infusion rate accordingly.
  • Avoid use in patients with known hypersensitivity to glucose solutions or excipients.
  • Monitor electrolytes, especially potassium, during prolonged administration.
  • Assess cardiac and renal function before large‑volume infusions.
  • Use aseptic technique to prevent contamination of the sterile solution.
  • Store the product according to manufacturer guidelines to maintain stability.

Avoid Interactions

Glucose monohydrate solutions can interact with other intravenous agents, influencing their efficacy or safety.

Avoid

  • Co‑administration with high‑dose insulin without appropriate glucose monitoring.
  • Simultaneous infusion with potassium chloride solutions that may precipitate.

Use with caution

  • Concurrent use of diuretics that can exacerbate electrolyte shifts.
  • Administration alongside catecholamines, as glucose may affect hemodynamic response.
  • Mixing with certain antibiotics that are unstable in high‑glucose environments.

Frequently Asked Questions

Glucosio S.A.L.F. is a sterile solution for injection that contains glucose monohydrate and is intended for intravenous administration.

It may be used to provide rapid carbohydrate energy during short‑term fasting, pre‑operative preparation, hypoglycemia correction, fluid resuscitation, and as part of total parenteral nutrition regimens.

Regulatory classifications list it as an excipient because its primary function is to supply glucose rather than to treat a specific disease.

Compatibility depends on the other drug; it is generally compatible with many solutions but may be unsuitable with certain antibiotics or electrolytes that are unstable in high‑glucose environments.

Monitoring blood glucose levels, serum electrolytes (especially potassium), and signs of fluid overload is recommended, particularly for prolonged infusions.

Patients with diabetes, renal impairment, cardiac failure, or known hypersensitivity to glucose solutions should be evaluated carefully before use.

The product should be stored according to the manufacturer’s instructions, typically in a controlled temperature environment away from direct sunlight to preserve sterility.

Common side effects include transient hyperglycemia, mild venous irritation, temporary changes in serum osmolality, and occasional nausea or abdominal discomfort.

Serious reactions may involve severe hyperglycemia, electrolyte disturbances such as hypokalemia, allergic or anaphylactoid responses, and fluid overload in patients with compromised cardiac function.

Regulatory status varies by jurisdiction; the product does not have a controlled schedule and may be available by prescription in many EU markets.

Use in pediatric patients should follow institutional protocols and consider age‑specific glucose requirements and monitoring.

The glucose monohydrate in the solution is rapidly absorbed into the bloodstream, serving as an immediate substrate for cellular metabolism and ATP production.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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