Product image of Glucosteril (Glucose Monohydrate) supplied by GNH India

Glucosteril

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucosteril (Glucose Monohydrate)

Glucosteril is a sterile intravenous solution containing glucose monohydrate as the active ingredient; the strength is not specified. It is supplied as a solution for injection and is marketed in the European Union. The product is classified as an excipient/solvent and is used under prescription for clinical situations that require rapid carbohydrate delivery and fluid replacement.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Glucosteril is employed in medical settings where immediate glucose provision and fluid balance are needed.

  • Treatment of acute hypoglycemia in adults and children
  • Component of parenteral nutrition regimens
  • Fluid and electrolyte replenishment during dehydration
  • Intra‑operative glucose support for surgical patients
  • Maintenance of glucose levels in neonatal intensive care
  • Emergency care for patients with low blood glucose due to trauma or illness

Side Effects

Glucosteril may be associated with both mild and more serious adverse reactions.

Common

  • Mild hyperglycemia
  • Local irritation or pain at the intravenous site
  • Transient peripheral edema
  • Nausea or mild gastrointestinal discomfort
  • Temporary increase in serum osmolality
  • Mild electrolyte shifts (e.g., potassium)

Serious

  • Severe hyperglycemia requiring medical intervention
  • Significant electrolyte imbalance (e.g., severe hypokalemia)
  • Anaphylactic or severe allergic reaction
  • Volume overload leading to pulmonary edema
  • Acute renal dysfunction in susceptible patients
  • Life‑threatening hyperosmolar state

Precautions & Warnings

Safety considerations are essential when administering Glucosteril.

  • Monitor blood glucose levels frequently during infusion
  • Assess fluid status and avoid excessive volume administration
  • Use caution in patients with renal, cardiac, or hepatic impairment
  • Adjust dosing for pediatric or neonatal patients under professional guidance
  • Verify compatibility with other intravenous solutions and catheters
  • Review pregnancy and lactation status before use
  • Discontinue if signs of severe hyperglycemia or allergic reaction appear

Avoid Interactions

Glucosteril can interact with other medications and solutions administered intravenously.

Avoid

  • Co‑administration of additional high‑dose dextrose or glucose solutions
  • Insulin overdose or mismatched insulin dosing
  • Medications that cause marked hypokalemia (e.g., high‑dose diuretics)
  • Hyperosmolar agents that may exacerbate fluid shifts

Use with caution

  • Loop or thiazide diuretics affecting electrolyte balance
  • Beta‑blockers that may mask hypoglycemia symptoms
  • Corticosteroids that increase glucose production
  • Vasopressors influencing circulatory dynamics
  • Other intravenous fluids requiring careful volume management

Frequently Asked Questions

Glucosteril is a sterile solution of glucose monohydrate intended for intravenous infusion. It is administered by a healthcare professional through a calibrated IV line.

Glucosteril is indicated for the treatment of acute hypoglycemia, as part of parenteral nutrition, and for fluid and electrolyte replenishment in patients requiring intravenous carbohydrate support.

The glucose monohydrate in Glucosteril is rapidly metabolized by cells, supplying immediate carbohydrate calories that can be used for energy production.

Blood glucose levels, serum electrolytes, and overall fluid balance should be regularly monitored while Glucosteril is being infused.

Yes, Glucosteril may be used in children when the dose is adjusted by a qualified healthcare professional based on weight and clinical condition.

Common side effects include mild hyperglycemia, local irritation at the IV site, transient peripheral edema, nausea, and mild electrolyte shifts.

Serious reactions such as severe hyperglycemia, significant electrolyte imbalance, anaphylaxis, or volume overload require immediate medical evaluation and discontinuation of the product.

Glucosteril should not be used in patients with a known hypersensitivity to glucose monohydrate or in those with uncontrolled fluid overload.

High‑dose dextrose solutions, insulin overdose, and drugs that cause marked electrolyte disturbances should be avoided during Glucosteril therapy.

Store Glucosteril at controlled room temperature, protect it from light, and discard any solution that has passed its expiration date or shows signs of contamination.

Pregnancy safety information for Glucosteril is not fully established; it should be used only if the potential benefit justifies the potential risk and under medical supervision.

If signs of an allergic reaction such as rash, itching, swelling, or difficulty breathing appear, the infusion should be stopped immediately and emergency medical care should be sought.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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