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Glucosteril Fresenius Kabi

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glucosteril Fresenius Kabi (Glucose Monohydrate)

Glucosteril Fresenius Kabi is an intravenous solution for injection that contains glucose monohydrate as its sole active ingredient. It is supplied in a liquid form without a specified concentration, intended for parenteral administration. Marketed in the European Union, this prescription‑only product is classified as a carbohydrate solution and is used as an energy source in clinical nutrition, often incorporated into infusion protocols to maintain glucose homeostasis during surgery or care.

Manufacturer / TM Owner

Fresenius Kabi Deutschland Gmbh

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Indications & Clinical Uses

Glucosteril is employed in clinical settings where rapid provision of glucose is required.

  • Supplementing carbohydrate calories in parenteral nutrition regimens.
  • Preventing hypoglycemia during peri‑operative periods.
  • Providing an immediate energy source for patients unable to receive enteral nutrition.
  • Supporting metabolic demands in critically ill or trauma patients.
  • Used as a diluent or carrier for compatible intravenous medications when glucose is needed.

Side Effects

When administered intravenously, Glucosteril may be associated with a range of observed effects.

Common

  • Transient increase in blood glucose levels.
  • Mild hyperosmolarity at high infusion rates.
  • Local irritation at the infusion site.
  • Nausea or vomiting if administered rapidly.

Serious

  • Severe hyperglycemia requiring medical intervention.
  • Electrolyte disturbances such as hyponatremia.
  • Fluid overload leading to pulmonary edema.
  • Allergic reactions including rash, urticaria, or anaphylaxis.

Precautions & Warnings

Clinicians should observe several precautions when prescribing Glucosteril to ensure patient safety.

  • Assess baseline blood glucose and adjust infusion rate accordingly.
  • Monitor serum electrolytes, especially sodium and potassium, during therapy.
  • Use caution in patients with renal or cardiac insufficiency due to risk of fluid overload.
  • Avoid rapid bolus administration; prefer controlled infusion.
  • Verify compatibility with other IV solutions before mixing.
  • Consider pregnancy status; data are limited.
  • Document infusion parameters in the patient record.

Avoid Interactions

Glucosteril can interact with other intravenous agents, influencing glucose balance or solution compatibility.

Avoid

  • Co‑administration with high‑dose insulin infusions without close glucose monitoring.
  • Mixing with calcium‑containing solutions that may precipitate.

Use with caution

  • Concurrent use of diuretics that affect electrolyte status.
  • Administration alongside hypertonic saline solutions.
  • Use with catecholamines that can increase glucose production.
  • Combining with other carbohydrate‑rich IV fluids may cause hyperglycemia.

Frequently Asked Questions

The active ingredient is glucose monohydrate, which provides a source of carbohydrate energy when administered intravenously.

Glucosteril is supplied as a sterile solution for injection and is given intravenously, typically through a controlled infusion pump.

It is used to supplement carbohydrate calories in parenteral nutrition, prevent peri‑operative hypoglycemia, and supply immediate energy to patients who cannot receive enteral feeding.

Blood glucose levels, serum electrolytes, and fluid balance should be regularly monitored to detect hyperglycemia, electrolyte shifts, or fluid overload.

Compatibility should be confirmed before mixing; it is generally compatible with many IV drugs but may precipitate when combined with calcium‑containing solutions.

Safety data in pregnancy are limited; clinicians should weigh potential benefits against unknown risks before use.

Common side effects include a temporary rise in blood glucose, mild hyperosmolarity, local infusion site irritation, and nausea if infused rapidly.

Serious reactions can include severe hyperglycemia, electrolyte disturbances, fluid overload leading to pulmonary edema, and allergic responses such as rash or anaphylaxis.

Yes, concurrent high‑dose insulin infusions require close glucose monitoring to avoid severe hypoglycemia or unpredictable glucose fluctuations.

Store the solution at controlled room temperature, protected from light, and discard any vial that shows particulate matter or discoloration.

The product is supplied without a specified concentration; the prescribing clinician determines the appropriate infusion rate based on patient needs.

It may be used in children when indicated, but dosing and monitoring must be individualized by a pediatric specialist.

Published by

GNH India Pharmaceuticals Limited

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Last updated:

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