Glucosum (Glucose)

Glucosum provides glucose for clinical situations where an immediate source of carbohydrate or osmotic balance is required.

• Intravenous administration to supply energy during surgery or critical care.
• Intra‑articular injection as an osmotic agent to aid joint lavage.
• Peri‑articular use to support tissue healing after orthopedic procedures.
• Diluent or carrier in parenteral nutrition formulations.
• Adjunct in diagnostic imaging procedures that require a glucose load.

Glucose administered as Glucosum is generally well tolerated, but adverse reactions can occur.

Common

• Transient hyperglycemia.
• Local irritation at the injection site.
• Mild nausea or vomiting.
• Headache or dizziness.

Serious

• Severe hyperglycemia leading to osmotic diuresis.
• Allergic reaction such as urticaria or anaphylaxis.
• Electrolyte imbalance, particularly hyponatremia.
• Volume overload in patients with cardiac failure.

When using Glucosum, clinicians should evaluate patient-specific factors and monitor for potential complications.

• Assess blood glucose levels before and after administration.
• Use caution in patients with diabetes mellitus or impaired glucose tolerance.
• Avoid rapid infusion in individuals at risk for fluid overload.
• Consider renal or hepatic impairment that may affect glucose metabolism.
• Monitor for signs of electrolyte disturbances during prolonged therapy.
• Evaluate for hypersensitivity history prior to intra‑articular use.

Glucosum may interact with other agents that influence glucose homeostasis or fluid balance.

Avoid

• Concomitant use of high‑dose insulin or other hypoglycemic agents without dose adjustment.
• Co‑administration with large volumes of dextrose‑containing solutions that could cause severe hyperglycemia.
• Simultaneous infusion of potassium‑rich solutions in patients prone to hyperkalemia.

Use with caution

• Medications that affect renal function such as NSAIDs or ACE inhibitors.
• Drugs that alter electrolyte status, for example loop diuretics.
• Anesthetic agents that may mask signs of glucose imbalance.