Product image of Glukos Fresenius Kabi (Glucose) supplied by GNH India

Glukos Fresenius Kabi

Active Ingredient:
Glucose
Origin:
EU

Glukos Fresenius Kabi (Glucose)

Glukos Fresenius Kabi is a sterile solution for injection that contains glucose as the sole active ingredient. It is supplied in a parenteral form for intravenous administration and is marketed in the European Union. The product is classified as an excipient/solvent and is used under prescription for clinical situations requiring rapid glucose delivery and fluid replacement.

Manufacturer / TM Owner

Fresenius Kabi Ab

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Indications & Clinical Uses

Glukos Fresenius Kabi is indicated for several clinical situations where rapid glucose supplementation and fluid balance are needed.

  • Treatment of hypoglycemia in emergency or perioperative settings.
  • Fluid and electrolyte replacement for patients with dehydration or electrolyte disturbances.
  • Component of parenteral nutrition regimens to provide an energy source.
  • Support during surgical procedures to maintain blood glucose levels.
  • Management of metabolic disorders requiring controlled glucose infusion.

Side Effects

Side effects of intravenous glucose solutions are generally related to the osmolar load and rapid shifts in blood glucose.

Common

  • Hyperglycemia when administered in excess.
  • Local irritation or pain at the infusion site.
  • Nausea or vomiting.
  • Headache.
  • Mild electrolyte imbalance (e.g., sodium, potassium).

Serious

  • Severe hyperglycemia leading to osmotic diuresis.
  • Fluid overload with pulmonary edema.
  • Hyperosmolar hyperglycemic state.
  • Allergic reaction or anaphylaxis to formulation components.

Precautions & Warnings

When using Glukos Fresenius Kabi, clinicians should consider several safety measures.

  • Assess baseline blood glucose and electrolyte status before infusion.
  • Adjust infusion rate in patients with renal or cardiac insufficiency to avoid fluid overload.
  • Monitor for signs of hyperglycemia during and after administration.
  • Use caution in patients with known hypersensitivity to any component of the solution.
  • Ensure proper aseptic technique to prevent catheter-related infections.
  • Verify compatibility with other intravenous medications before co‑administration.

Avoid Interactions

Glucose solutions can interact with other therapies, influencing efficacy or safety.

Avoid

  • Co‑administration with high‑dose insulin without appropriate monitoring, which may precipitate severe hypoglycemia.
  • Simultaneous infusion of hypertonic solutions that could exacerbate hyperosmolar states.

Use with caution

  • Concurrent use of diuretics, which may alter fluid and electrolyte balance.
  • Administration alongside potassium‑containing solutions; monitor serum potassium levels.
  • Use with catecholamines or glucocorticoids that can raise blood glucose.
  • Combination with other carbohydrate‑containing parenteral fluids; adjust total glucose load accordingly.

Frequently Asked Questions

Glukos Fresenius Kabi is primarily indicated for the treatment of hypoglycemia, fluid and electrolyte replacement, and as a component of parenteral nutrition regimens.

The product is supplied as a sterile solution for injection and is administered intravenously under the supervision of a qualified healthcare professional.

Use in pediatric patients should be based on clinical judgment, with careful dosing and monitoring of blood glucose and fluid status.

Blood glucose levels, electrolytes, and fluid balance should be monitored regularly to detect hyperglycemia, electrolyte shifts, or fluid overload.

Compatibility should be assessed before co‑administration; some drugs may require separate lines or specific timing to avoid incompatibility.

Common side effects include transient hyperglycemia, local infusion site irritation, nausea, headache, and mild electrolyte disturbances.

The rate should be adjusted in patients with renal or cardiac impairment, or when signs of fluid overload or hyperglycemia develop.

The formulation details, including the presence of preservatives, are provided in the product’s official labeling and should be reviewed before use.

Patients with known hypersensitivity to any component of the solution should be evaluated carefully, and alternative therapies considered if necessary.

Yes, it is often used intraoperatively to maintain blood glucose levels and provide fluid support, following appropriate dosing protocols.

The product should be stored according to the manufacturer’s instructions, typically in a controlled temperature environment away from light.

In case of overdose, monitor the patient for signs of severe hyperglycemia and fluid overload, and manage according to standard clinical guidelines.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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