Product image of Glukosalina Iii (Sodium Chloride, Glucose) supplied by GNH India

Glukosalina Iii

Active Ingredient:
Sodium Chloride, Glucose
Origin:
EU

Glukosalina Iii (Sodium Chloride, Glucose)

Glukosalina III is an intravenous solution for injection that contains sodium chloride and glucose. The product is supplied as a sterile liquid preparation, marketed in the European Union and available by prescription. It provides both electrolyte (sodium chloride) and carbohydrate (glucose) components in a single formulation, intended to support fluid balance and energy needs when administered intravenously in hospitals or emergency settings or urgent care environments.

Manufacturer / TM Owner

Hrvatski Zavod Za Transfuzijsku Medicinu

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Indications & Clinical Uses

Glukosalina III is indicated for clinical situations that require rapid restoration of fluid volume, electrolyte balance, or glucose levels. It is commonly used in hospital settings, including emergency departments, intensive care units, and perioperative care.

  • Fluid replacement in dehydration or blood loss.
  • Maintenance of electrolyte balance during surgery or critical illness.
  • Treatment of hypoglycemia when oral glucose is not feasible.
  • Provision of caloric support in patients unable to receive enteral nutrition.
  • Dilution and administration of other intravenous medications as a compatible carrier.
  • Correction of electrolyte disturbances such as hyponatremia during acute care.

Side Effects

The safety profile of Glukosalina III reflects the typical reactions associated with intravenous electrolyte and glucose solutions.

Common

  • Mild irritation at the injection site.
  • Transient increase in blood glucose levels.
  • Slight electrolyte shifts causing temporary nausea.
  • Mild headache or dizziness during infusion.
  • Temporary feeling of warmth or flushing at the infusion site.
  • Occasional mild metallic taste if solution contacts oral mucosa.

Serious

  • Hypernatremia from excessive sodium administration.
  • Severe hypoglycemia if glucose is insufficiently balanced.
  • Allergic reactions such as rash, itching, or anaphylaxis.
  • Fluid overload leading to pulmonary edema in patients with compromised cardiac function.
  • Severe electrolyte imbalance causing cardiac arrhythmias.
  • Risk of infection if aseptic technique is not maintained during administration.

Precautions & Warnings

When using Glukosalina III, clinicians should observe specific precautions to minimize risks and ensure appropriate therapy.

  • Verify patient’s electrolyte status and serum sodium levels before infusion.
  • Adjust infusion rate in patients with cardiac, renal, or hepatic impairment.
  • Monitor blood glucose regularly during and after administration.
  • Use aseptic technique and inspect the solution for particulate matter or discoloration.
  • Avoid rapid large-volume infusions unless clinically indicated.
  • Assess for any history of hypersensitivity to sodium chloride or glucose solutions.
  • Document volume and concentration administered in the patient record.

Avoid Interactions

Glukosalina III may interact with other intravenous therapies or medications that affect fluid, electrolyte, or glucose balance.

Avoid

  • Co-administration with hypertonic saline solutions, which can cause excessive sodium load.
  • Simultaneous infusion of high-dose insulin without glucose supplementation, increasing risk of hypoglycemia.
  • Mixing with incompatible drugs that precipitate in the presence of chloride ions.
  • Concurrent infusion of potassium chloride solutions without proper monitoring can lead to dangerous potassium accumulation.

Use with caution

  • Concurrent use of diuretics, requiring close monitoring of electrolyte status.
  • Administration alongside vasopressors, as fluid shifts may alter hemodynamic response.
  • Use with other carbohydrate-containing solutions, to avoid hyperglycemia.
  • When combined with blood products, monitor for changes in serum sodium and glucose to prevent imbalances.

Frequently Asked Questions

Glukosalina III contains sodium chloride and glucose dissolved in a sterile aqueous solution for intravenous administration.

It is commonly used in hospitals, emergency departments, intensive care units, and perioperative areas for fluid and electrolyte management.

Yes, the glucose component can help raise blood sugar levels when oral intake is not possible.

No, it is a prescription‑only medication and must be administered by a qualified healthcare professional.

Patients should have their serum electrolytes, sodium, and blood glucose checked before and during the infusion.

Store the solution at controlled room temperature, protected from light, and keep the container sealed until use.

Common side effects include mild injection‑site irritation, transient rise in blood glucose, and temporary nausea.

Adjust the rate in patients with cardiac, renal, or hepatic impairment, or when large fluid volumes are required.

It can be used as a compatible carrier for some drugs, but incompatibilities with certain solutions (e.g., hypertonic saline) should be avoided.

Signs of hypernatremia, severe hypoglycemia, allergic reactions such as rash or anaphylaxis, and fluid overload leading to pulmonary edema are serious and need prompt evaluation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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