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Glukose Sad

Active Ingredient:
Glucose Monohydrate
Origin:
EU

Glukose Sad (Glucose Monohydrate)

Glukose Sad is an intravenous (IV) solution containing glucose monohydrate as its sole active ingredient. It is supplied in a sterile liquid form for infusion, and is marketed within the European Union. The product provides a readily available source of carbohydrate for patients requiring parenteral nutrition or rapid correction of low blood glucose, and is classified as a nutrient excipient and is intended for use under medical supervision.

Manufacturer / TM Owner

Amgros I/S

1
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Indications & Clinical Uses

Glukose Sad is used in clinical settings where an immediate source of glucose is required.

  • Management of acute hypoglycemia in hospitalized patients.
  • Component of parenteral nutrition formulations.
  • Support during surgical procedures to maintain blood glucose levels.
  • Fluid and electrolyte replacement when combined with appropriate electrolytes.
  • Energy source for patients unable to tolerate oral intake.

Side Effects

Intravenous administration of glucose monohydrate can be associated with a range of observed effects, most of which are related to the metabolic and vascular response to the solution.

Common

  • Transient hyperglycemia.
  • Local irritation or phlebitis at the infusion site.
  • Mild nausea.
  • Electrolyte shifts such as low potassium.
  • Headache.

Serious

  • Severe hyperglycemia leading to osmotic diuresis.
  • Hypersensitivity or allergic reaction.
  • Hyperosmolar coma in susceptible patients.
  • Rapid fluid overload causing pulmonary edema.

Precautions & Warnings

Because Glukose Sad delivers a concentrated carbohydrate load directly into the bloodstream, several precautions should be observed before and during its use.

  • Verify blood glucose level before infusion to avoid excessive rise.
  • Adjust infusion rate in patients with renal or cardiac insufficiency.
  • Use aseptic technique to prevent contamination.
  • Monitor electrolytes, especially potassium and sodium, during therapy.
  • Avoid use in patients with known hypersensitivity to glucose solutions.
  • Consider contraindication in uncontrolled diabetes mellitus.

Avoid Interactions

Glucose solutions can interact with other medications or clinical conditions, influencing their efficacy or safety.

Avoid

  • Co-administration with rapid‑acting insulin without dose adjustment.
  • Simultaneous infusion of high‑concentration potassium chloride.
  • Use with hypertonic saline solutions that may exacerbate hyperosmolar states.

Use with caution

  • Concurrent use of diuretics that affect fluid balance.
  • Administration alongside beta‑blockers in patients prone to hypoglycemia.
  • Overlap with medications that affect serum potassium, such as ACE inhibitors.

Frequently Asked Questions

Glukose Sad is an intravenous solution whose only active ingredient is glucose monohydrate, providing a sterile source of carbohydrate for infusion.

It is administered through a sterile IV line by a qualified health professional, following standard infusion protocols and monitoring.

Common situations include treatment of acute hypoglycemia, inclusion in parenteral nutrition regimens, and maintenance of blood glucose during surgery or critical illness.

Typical side effects are transient hyperglycemia, mild nausea, local irritation or phlebitis at the infusion site, headache, and temporary electrolyte shifts such as low potassium.

Serious reactions can include severe hyperglycemia with osmotic diuresis, hypersensitivity or allergic response, hyperosmolar coma in vulnerable patients, and rapid fluid overload leading to pulmonary edema.

Precautions include checking baseline blood glucose, assessing renal and cardiac function, using aseptic technique, monitoring electrolytes, and confirming no known hypersensitivity to glucose solutions.

Blood glucose should be measured before infusion, periodically during the infusion, and after completion to ensure levels remain within the target range.

It can be used in diabetic patients only under close medical supervision, with careful adjustment of insulin or other glucose‑lowering therapies to avoid excessive hyperglycemia.

Rapid‑acting insulin doses should be adjusted, high‑concentration potassium chloride infusions should be avoided, and caution is advised with diuretics, beta‑blockers, and ACE inhibitors.

Store the unopened solution at controlled room temperature, protected from light, and discard any product that appears discolored or cloudy.

Once opened, the bag should be used within the time frame recommended by the manufacturer, typically within 24 hours if kept under aseptic conditions.

Glukose Sad is generally supplied to healthcare facilities and requires a prescription or medical order for use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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