Glukoza Braun (Glucose Monohydrate)

Glukoza Braun is indicated for several clinical situations where rapid glucose delivery is required.

• Treatment of hypoglycemia when oral glucose is not feasible.
• Component of parenteral nutrition regimens for patients unable to receive enteral feeding.
• Fluid and electrolyte replacement in conjunction with other intravenous solutions.
• Energy source during perioperative care or critical illness.
• Support for patients with metabolic disorders that limit endogenous glucose production.

Adverse reactions to Glukoza Braun are generally related to the intravenous administration of a carbohydrate solution and may vary in frequency.

Common

• Hyperglycemia due to excess glucose load.
• Local irritation or pain at the injection site.
• Nausea or vomiting.
• Headache.

Serious

• Severe hyperglycemia with osmotic diuresis.
• Allergic or anaphylactic reactions such as rash, itching, or respiratory distress.
• Electrolyte imbalance, particularly hyponatremia, when administered in large volumes.
• Phlebitis or thrombophlebitis at the infusion site.

When prescribing Glukoza Braun, clinicians should evaluate patient-specific factors and monitor relevant parameters to reduce the risk of complications.

• Assess blood glucose levels before and during infusion to avoid hyperglycemia.
• Use caution in patients with diabetes mellitus or impaired glucose tolerance.
• Adjust infusion rate in individuals with renal or hepatic dysfunction.
• Monitor fluid balance and electrolytes, especially sodium and potassium.
• Avoid rapid administration in neonates and infants.
• Consider compatibility with other intravenous drugs to prevent precipitation.

Glukoza Braun may interact with other medications administered intravenously or affect the pharmacodynamics of certain drugs.

Avoid

• Concurrent use of high‑dose insulin without appropriate glucose monitoring.
• Co‑administration with other hypertonic carbohydrate solutions that could exacerbate hyperglycemia.

Use with caution

• Loop diuretics, which may increase the risk of electrolyte disturbances.
• Catecholamines (e.g., epinephrine) that raise blood glucose levels.
• Sodium‑containing IV fluids, which may contribute to fluid overload.
• Certain antibiotics (e.g., aminoglycosides) that require careful renal monitoring when large fluid volumes are given.