Glutaferro (Ferrous (Ii) Glycine Sulfate Complex)

Glutaferro is indicated for individuals who need additional iron to maintain normal physiological functions.

• Management of iron deficiency diagnosed by a healthcare professional.
• Prevention of iron deficiency anemia in at‑risk populations such as menstruating women, children, and the elderly.
• Support during periods of increased iron demand, for example pregnancy, lactation, or growth spurts.
• Adjunct to dietary measures for vegetarians, vegans, or individuals with limited iron intake.
• Assistance for athletes or persons with high physical activity who experience iron loss through sweat or hemolysis.

Like other oral iron preparations, Glutaferro may cause side effects, most of which are mild and reversible.

Common

• Nausea or upset stomach.
• Constipation or loose stools.
• Darkened stools.
• Abdominal cramping or discomfort.
• Metallic taste in the mouth.

Serious

• Allergic reactions such as rash, itching, or swelling.
• Difficulty breathing or wheezing.
• Severe abdominal pain with vomiting.
• Signs of iron overload (e.g., joint pain, fatigue).

Appropriate use of Glutaferro requires attention to certain precautions to minimize risk and ensure effectiveness.

• Not for individuals diagnosed with hereditary hemochromatosis or other iron‑storage disorders.
• Keep out of reach of children; accidental ingestion can be hazardous.
• Consult a healthcare professional before use if pregnant, breastfeeding, or having chronic medical conditions.
• Do not exceed the recommended daily amount without medical advice.
• Periodically monitor iron status (e.g., ferritin, hemoglobin) during prolonged supplementation.
• Avoid taking with foods or beverages that strongly inhibit iron absorption, such as coffee, tea, or high‑calcium products.
• Store in a dry place at room temperature, away from direct sunlight.

Glutaferro can interact with several medications and nutrients that affect iron absorption or increase the risk of adverse effects.

Avoid

• Antacids containing aluminum, magnesium, or calcium.
• Calcium supplements or calcium‑rich foods taken simultaneously.
• Tetracycline antibiotics (e.g., doxycycline).
• Fluoroquinolone antibiotics (e.g., ciprofloxacin).
• Certain thyroid hormone preparations (e.g., levothyroxine) when taken together.

Use with caution

• Levothyroxine – separate dosing by at least 4 hours.
• Levodopa – monitor for reduced efficacy.
• Bisphosphonates – separate administration to avoid chelation.
• Multivitamins containing iron – avoid duplicate dosing.
• Foods high in phytates (e.g., legumes, whole grains) – may reduce absorption, consider timing.