Glycerine Sopreli Volwassenen (Glycerol)

Glycerine Sopreli Volwassenen suppositories are primarily used to facilitate the evacuation of the bowels in adults who experience occasional constipation.

• To soften stool and promote a natural, gentle rectal evacuation.
• As a short‑term aid for occasional constipation when dietary measures are insufficient.
• To assist in bowel preparation before minor medical examinations that require an empty rectum.
• For use in patients who prefer a non‑oral, locally acting laxative option.
• Occasionally recommended for relief of mild fecal impaction under medical supervision.
• To provide a non‑systemic option for patients who cannot tolerate oral laxatives.

Side effects of glycerol suppositories are generally mild because the active ingredient works locally in the rectum.

Common

• Mild rectal irritation or burning sensation.
• Slight spotting of stool or mucus after insertion.
• Temporary increase in bowel movement frequency.
• Mild discomfort during insertion that resolves quickly.
• Small amount of liquid stool following the dose.
• Transient feeling of urgency to defecate.
• Occasional mild anal itching after use.

Serious

• Persistent abdominal pain or cramping.
• Severe rectal bleeding.
• Signs of allergic reaction such as rash, itching, or swelling.
• Persistent diarrhea lasting more than 24 hours.
• Signs of electrolyte imbalance such as dizziness or muscle cramps.
• Severe abdominal distension.
• Signs of infection such as fever or foul‑smelling discharge.

When using Glycerine Sopreli Volwassenen, certain precautions help ensure safe and effective use.

• Do not use if you have a known allergy to glycerol or any excipients listed on the package.
• Avoid insertion if you have an active rectal bleeding disorder or severe hemorrhoids.
• Use only as directed; excessive or repeated use may lead to electrolyte imbalance.
• Consult a healthcare professional before use during pregnancy, breastfeeding, or in children under 18.
• Do not use the suppository if the packaging is damaged or the product appears discolored.
• Store at room temperature away from direct heat and moisture.
• Keep out of reach of children.

Glycerol suppositories have limited systemic absorption, but they can interact with certain medications or conditions when used concurrently.

Avoid

• Concurrent use with strong stimulant laxatives, which may cause excessive bowel movements.
• Use in patients receiving intravenous fluids containing high sodium, as glycerol can affect fluid balance.
• Insertion after recent rectal surgery or trauma.
• Do not use if you have an active gastrointestinal infection, as glycerol may exacerbate symptoms.

Use with caution

• Combination with oral osmotic laxatives; monitor for signs of dehydration.
• Use in individuals taking diuretics; watch electrolyte levels.
• Patients with chronic kidney disease; consult a physician before use.
• When combined with anticholinergic drugs, monitor for reduced intestinal motility.