Product image of Kanova Niños (Glycerol) supplied by GNH India

Kanova Niños

Active Ingredient:
Glycerol
Origin:
EU

Kanova Niños (Glycerol)

Glycerol, the active ingredient in Kanova Niños, is an osmotic laxative presented as an unspecified strength suppository for rectal use. It works locally in the intestinal tract to draw water into the lumen, softening stool and facilitating evacuation, thereby providing relief from constipation in pediatric patients.

GNH India supplies Kanova Niños as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality manufacturing standards and reliable distribution across global markets, and timely delivery to meet patient needs.

Manufacturer / TM Owner

Lainco S.A.

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Indications & Clinical Uses

Kanova Niños, an osmotic laxative, is used to treat constipation in the pediatric population.

  • Constipation: softens stool and promotes bowel movement in children.
  • Functional constipation: improves stool consistency and reduces straining.
  • Encopresis associated with constipation: facilitates evacuation to help manage fecal leakage.

How It Works

  • Glycerol creates an osmotic gradient within the intestinal lumen by attracting water from surrounding tissues. The increased water content softens the fecal mass, expands the stool volume, and stimulates rectal stretch receptors, which trigger peristaltic activity and promote evacuation. Its action is localized to the colon and does not involve systemic absorption. This local effect provides rapid relief without significant systemic exposure.

Side Effects

Glycerol suppositories may be associated with the following adverse reactions.

Common Side Effects

  • Rectal irritation: mild burning or discomfort at the application site.
  • Diarrhea: loose stools due to excess water in the colon.
  • Abdominal cramping: transient cramps following administration.
  • Nausea: occasional feeling of nausea after use.

Serious or Rare Side Effects

  • Severe rectal bleeding: unexpected bleeding requiring medical attention.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Electrolyte imbalance: rare disturbance from excessive fluid loss.

Precautions & Warnings

Before using Kanova Niños, consider the following precautions.

  • Age restriction: intended for pediatric use; follow age guidelines on the label.
  • Underlying conditions: avoid in patients with intestinal obstruction or perforation.
  • Fluid balance: monitor for dehydration if diarrhea occurs.
  • Concomitant laxatives: do not combine with other osmotic or stimulant laxatives without medical advice.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Glycerol may interact with certain medications or substances.

Major Interactions (Avoid)

  • Antidiarrheal agents (e.g., loperamide): may counteract glycerol’s laxative effect.
  • High‑dose oral rehydration solutions: can exacerbate fluid shifts when combined.

Moderate Interactions (Monitor Closely)

  • Mineral oil: concurrent use may reduce absorption of fat‑soluble vitamins.
  • Certain antibiotics (e.g., tetracyclines): glycerol may alter gastrointestinal transit, affecting drug absorption.
  • Oral electrolyte supplements: monitor electrolyte status if prolonged use of glycerol occurs.

Frequently Asked Questions

Kanova Niños is a rectally administered glycerol suppository indicated for the relief of constipation in children. It works by softening stool and promoting natural evacuation, providing a non‑systemic option for pediatric bowel management.

Glycerol acts as an osmotic agent; when placed in the rectum it draws water from surrounding tissues into the intestinal lumen. The added fluid softens the stool, increases its volume, and stimulates stretch receptors that trigger peristalsis, facilitating bowel movement.

The appropriate dose of Kanova Niños is determined by a qualified healthcare professional based on the child’s age, weight, and severity of constipation. The prescriber will select the correct number of suppositories and frequency of administration.

Safety data for glycerol suppositories in pregnancy or lactation are limited. Use is generally avoided unless clearly indicated by a physician. Women who are pregnant or breastfeeding should consult their healthcare provider before using the product.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Kanova Niños provides a locally acting, non‑systemic option compared with oral agents such as lactulose or polyethylene glycol, which require gastrointestinal absorption. Unlike mineral oil, glycerol does not carry a risk of lipid aspiration and has a rapid onset of action when administered rectally.

Store the suppositories at temperatures below 25 °C in their original packaging, protecting them from moisture, heat and direct sunlight. Keep out of reach of children and avoid crushing or breaking the suppository before use.

Kanova Niños is inserted rectally, typically with gloved fingers or an applicator, according to the prescriber’s instructions. The child should lie on their side with knees drawn toward the chest to facilitate placement, and remain in that position for a few minutes to allow the suppository to melt.

Serious adverse events, although rare, include severe rectal bleeding and allergic reactions such as rash, swelling or anaphylaxis. Prompt medical attention is required if any of these symptoms occur after administration.

Kanova Niños should be avoided in children with known hypersensitivity to glycerol, those with intestinal obstruction, perforation, or severe inflammatory bowel disease, and in patients who are currently using other rectal laxatives without medical guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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