Goganza (Sodium Hydrogen Carbonate, Potassium Chloride, Sodium Chloride, Macrogol 3350)

Goganza is indicated for situations where fluid and electrolyte loss requires rapid replacement.

• Dehydration caused by acute diarrhea in children and adults.
• Electrolyte replacement during gastroenteritis or other fluid‑losing conditions.
• Prevention of dehydration in at‑risk groups such as the elderly or those with chronic illnesses.
• Support of rehydration therapy when oral intake of fluids is limited.
• Adjunctive use in preparation for diagnostic procedures that may cause fluid shifts.

The safety profile of Goganza reflects the components of the electrolyte solution and the osmotic laxative effect of macrogol 3350.

Common

• Mild abdominal discomfort or bloating.
• Transient nausea or vomiting.
• Loose stools or mild diarrhea.
• Temporary headache.
• Mild thirst.
• Mild fatigue.

Serious

• Severe electrolyte imbalance (e.g., hypernatremia, hyperkalemia).
• Persistent vomiting leading to further dehydration.
• Allergic reactions such as rash, itching, or swelling.
• Signs of severe dehydration despite use (e.g., dizziness, rapid heartbeat).
• Seizures due to electrolyte disturbances.
• Acute kidney injury.

When using Goganza, certain precautions help ensure safe and effective rehydration, especially in vulnerable populations.

• Assess electrolyte status before initiating therapy in patients with known renal or cardiac disease.
• Use caution in individuals with severe diarrhea, as rapid fluid shifts may occur.
• Do not exceed the recommended volume without medical supervision.
• Monitor for signs of over‑hydration, particularly in infants and the elderly.
• Avoid use in patients with known hypersensitivity to any component of the formulation.
• Pregnant or breastfeeding individuals should consult a healthcare professional before use.

Goganza may interact with other medications or substances that affect fluid balance or electrolyte levels.

Avoid

• Loop diuretics (e.g., furosemide) that can exacerbate electrolyte loss.
• Sodium‑containing laxatives or other oral rehydration products that may cause excess sodium intake.
• Medications that prolong the QT interval when combined with electrolyte disturbances.

Use with caution

• ACE inhibitors or ARBs, as shifts in potassium may require monitoring.
• Antacids containing sodium or potassium, which could alter electrolyte balance.
• Oral antibiotics for gastrointestinal infections, to ensure adequate absorption of the solution.