Product image of Gonasi Set (Human Chorionic Gonadotropin) supplied by GNH India

Gonasi Set

Active Ingredient:
Human Chorionic Gonadotropin
Origin:
EU

Gonasi Set (Human Chorionic Gonadotropin)

Gonasi Set contains the active ingredient human chorionic gonadotropin (hCG) and is supplied in an injectable form for intramuscular or subcutaneous administration. It is marketed in the European Union and is available by prescription only. The product mimics luteinizing hormone activity to support ovulation and luteal phase function in fertility treatment and is also used in specific pediatric indications.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

Gonasi Set is prescribed for several reproductive and endocrine indications. It is used under medical supervision to assist patients undergoing fertility procedures.

  • Induction of ovulation in women with anovulatory infertility.
  • Luteal phase support in assisted reproductive technology such as IVF.
  • Treatment of cryptorchidism (undescended testicle) in male infants.
  • Management of hypogonadotropic hypogonadism when gonadotropin therapy is indicated.
  • Adjunct therapy in certain cases of male infertility to stimulate testosterone production.

Side Effects

Side effects of Gonasi Set vary in frequency and severity. Patients should be aware of both common and serious reactions.

Common

  • Injection site pain, redness, or swelling.
  • Headache or mild dizziness.
  • Nausea or abdominal discomfort.
  • Breast tenderness or swelling.
  • Transient flu‑like symptoms.

Serious

  • Allergic reactions such as rash, itching, or anaphylaxis.
  • Ovarian hyperstimulation syndrome (OHSS) in women.
  • Thromboembolic events (rare).

Precautions & Warnings

Before using Gonasi Set, clinicians consider several safety factors. Patients should follow medical guidance and report any concerns.

  • Assess for contraindications such as known hypersensitivity to hCG.
  • Evaluate risk of ovarian hyperstimulation syndrome in women undergoing fertility treatment.
  • Monitor for signs of thromboembolic disease, especially in patients with clotting disorders.
  • Use caution in patients with uncontrolled hypertension or cardiovascular disease.
  • Discuss potential effects on hormone‑dependent tumors.
  • Ensure appropriate dosing and timing in pediatric cryptorchidism cases.

Avoid Interactions

Gonasi Set may interact with other medications or substances. Some combinations should be avoided, while others require careful monitoring.

Avoid

  • Concurrent use of estrogen‑containing oral contraceptives, which can diminish hCG effectiveness.
  • High‑dose corticosteroids that may alter hormonal response.

Use with caution

  • Anticoagulants, due to potential increased risk of thrombosis.
  • Thyroid hormone replacement, as hCG can affect thyroid function tests.
  • Medications that influence the renin‑angiotensin system, requiring blood pressure monitoring.
  • Other gonadotropins or fertility drugs, to prevent overstimulation.

Frequently Asked Questions

The active ingredient in Gonasi Set is human chorionic gonadotropin (hCG), a hormone that mimics luteinizing hormone activity.

Gonasi Set is administered by intramuscular or subcutaneous injection, typically in a clinical setting under physician supervision.

It is prescribed for women undergoing fertility treatment, for luteal phase support in assisted reproductive technology, and for male infants with cryptorchidism.

Concurrent use of estrogen‑containing oral contraceptives may reduce the effectiveness of hCG and is generally avoided.

Common side effects include injection site pain, headache, nausea, breast tenderness, and mild flu‑like symptoms.

Serious reactions include allergic responses such as rash or anaphylaxis, ovarian hyperstimulation syndrome, and rare thromboembolic events.

Gonasi Set is used in specific fertility protocols under medical guidance; its safety in ongoing pregnancy is not established and should be discussed with a healthcare provider.

hCG stimulates the corpus luteum to produce progesterone, helping maintain the uterine lining during the luteal phase of the menstrual cycle.

Patients are typically monitored for ovarian response, hormone levels, blood pressure, and signs of ovarian hyperstimulation or thrombosis.

In certain cases, hCG can be used to stimulate testosterone production in men with hypogonadotropic hypogonadism, but this is determined by a specialist.

Yes, Gonasi Set is a prescription‑only medication in the European Union.

If a dose is missed, contact your prescribing clinician for instructions; do not self‑adjust the schedule.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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