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Gonasi Set

Active Ingredient:
Human Chorionic Gonadotropin
Origin:
EU

Gonasi Set (Human Chorionic Gonadotropin)

Gonasi Set is a prescription medication that contains the hormone human chorionic gonadotropin (hCG) for intramuscular or subcutaneous injection. It is supplied in a sterile injectable form and is marketed in the European Union. The product is classified as a gonadotropin hormone used in fertility and reproductive health management.

Manufacturer / TM Owner

Ibsa Farmaceutici Italia

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Indications & Clinical Uses

Gonasi Set is indicated for several reproductive‑health indications in both women and men.

  • Induction of ovulation in assisted reproductive techniques such as in vitro fertilization.
  • Support of the luteal phase in women with luteal‑phase deficiency.
  • Stimulation of spermatogenesis in males with hypogonadotropic hypogonadism.
  • Treatment of undescended testis (cryptorchidism) in pediatric patients.
  • Adjunct therapy in certain cases of male testosterone deficiency.

Side Effects

Side‑effect profiles for Gonasi Set include both frequently observed reactions and less common but serious events.

Common

  • Injection‑site pain or bruising.
  • Headache.
  • Fatigue or mild weakness.
  • Nausea or mild abdominal discomfort.
  • Mild ovarian swelling in women.

Serious

  • Ovarian hyperstimulation syndrome (OHSS) with rapid abdominal distension.
  • Severe allergic reaction including anaphylaxis.
  • Thromboembolic events such as deep‑vein thrombosis.
  • Acute abdominal pain indicating possible ovarian torsion.
  • Persistent high testosterone levels in men requiring medical review.

Precautions & Warnings

Before initiating Gonasi Set, clinicians should evaluate several safety considerations.

  • Confirm that the patient is not pregnant before administration.
  • Assess ovarian response risk to avoid OHSS.
  • Review thyroid function, as hCG can affect thyroid hormone levels.
  • Evaluate for known hypersensitivity to hCG or formulation components.
  • Consider underlying cardiovascular or clotting disorders.
  • Monitor testosterone levels in male patients during therapy.

Avoid Interactions

Gonasi Set may interact with other medicines, requiring avoidance or careful monitoring.

Avoid

  • Estrogen‑containing oral contraceptives, which may reduce hCG efficacy.
  • GnRH agonists or antagonists that suppress pituitary hormone release.
  • High‑dose androgenic steroids that can interfere with testosterone response.

Use with caution

  • Anticoagulant therapy, because OHSS can increase clot risk.
  • Thyroid hormone replacement, as hCG may stimulate thyroid activity.
  • Corticosteroids, which could mask signs of an allergic reaction.

Frequently Asked Questions

Gonasi Set is a prescription injectable that contains human chorionic gonadotropin (hCG). hCG mimics luteinizing hormone (LH) activity, stimulating ovulation and supporting the luteal phase in women, and promoting testosterone production and spermatogenesis in men.

It is prescribed for ovulation induction in assisted reproductive techniques, luteal‑phase support, induction of spermatogenesis in hypogonadotropic hypogonadism, treatment of cryptorchidism, and as adjunct therapy in certain cases of male testosterone deficiency.

Gonasi Set is given by a healthcare professional as an intramuscular or subcutaneous injection, following the dosing schedule determined by the treating physician.

Gonasi Set is not intended for use in women who are already pregnant. Pregnancy status should be confirmed before each administration.

Common side effects include injection‑site pain or bruising, headache, fatigue, mild nausea or abdominal discomfort, and mild ovarian swelling in women.

Serious reactions may include ovarian hyperstimulation syndrome, severe allergic reactions such as anaphylaxis, thromboembolic events, acute abdominal pain suggesting ovarian torsion, and unexpectedly high testosterone levels in men.

Precautions include confirming the patient is not pregnant, assessing risk of ovarian hyperstimulation, reviewing thyroid function, checking for hypersensitivity to hCG, evaluating cardiovascular or clotting disorders, and planning regular monitoring of hormone levels.

Yes. Gonasi Set should be avoided with estrogen‑containing oral contraceptives, GnRH agonists/antagonists, and high‑dose androgenic steroids. Use with caution when combined with anticoagulants, thyroid hormone replacement, or corticosteroids.

The product should be stored in a refrigerator (2‑8 °C) protected from light. Do not freeze. Allow the vial to reach room temperature before injection, following the manufacturer’s instructions.

Yes, Gonasi Set is marketed in the European Union and is available by prescription in accordance with EU regulatory standards.

Gonasi Set may be used to stimulate endogenous testosterone production in men with hypogonadotropic hypogonadism, but it is not a primary therapy for primary testosterone deficiency.

Monitoring typically includes serial ultrasound of the ovaries in women, serum estradiol and progesterone levels, thyroid function tests, and testosterone levels in men, as well as observation for signs of OHSS or allergic reactions.

Published by GNH India Pharmaceuticals Limited

Last updated:

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