Gopain (Ibuprofen, Paracetamol)

Gopain is indicated for the temporary relief of several common conditions that involve pain, fever, or inflammation.

• Mild to moderate headache or tension‑type headache
• Dental pain after procedures or tooth extraction
• Musculoskeletal aches such as back strain or sprain
• Fever associated with viral or mild bacterial infections
• Minor postoperative discomfort following minor surgery
• Menstrual cramps (dysmenorrhea) for short‑term relief
• Sore throat pain when caused by irritation or infection
• Joint pain from mild osteoarthritis flare‑ups

The safety profile of Gopain reflects the known effects of both ibuprofen and paracetamol, with most reactions being mild and reversible. These effects are dose‑related and may vary with individual sensitivity, age, or concurrent use of other medications.

Common

• Upset stomach or dyspepsia
• Nausea or mild vomiting
• Headache
• Dizziness or light‑headed feeling
• Mild abdominal discomfort
• Temporary increase in blood pressure

Serious

• Signs of allergic reaction such as rash, swelling, or difficulty breathing
• Liver enzyme elevation or jaundice indicating possible hepatic injury
• Severe stomach pain or black/tarry stools suggesting gastrointestinal bleeding
• Kidney function impairment manifested by reduced urine output
• Unexplained bruising or bleeding indicating clotting changes

When using Gopain, certain precautions should be observed to minimize risk and ensure safe use.

• Do not exceed the recommended daily dose of ibuprofen and paracetamol combined.
• Avoid use in individuals with known hypersensitivity to NSAIDs or acetaminophen.
• Use caution if you have a history of stomach ulcers, gastrointestinal bleeding, or chronic liver disease.
• Consult a healthcare professional before use during pregnancy, breastfeeding, or in children under the recommended age.
• Limit alcohol consumption while taking the product, as it may increase liver strain.
• Discontinue and seek medical advice if symptoms persist beyond a few days or worsen.

Gopain may interact with other medicines, and awareness of these interactions helps prevent adverse effects.

Avoid

• Concurrent use with other NSAIDs (e.g., ibuprofen, naproxen, diclofenac) which can increase risk of gastrointestinal bleeding.
• Taking additional paracetamol‑containing products, which may lead to hepatotoxicity.
• Use with anticoagulants such as warfarin or direct oral anticoagulants without medical supervision.

Use with caution

• ACE inhibitors or diuretics, as ibuprofen may reduce their antihypertensive effect.
• Lithium therapy, because NSAIDs can increase lithium levels.
• Certain antiepileptic drugs (e.g., carbamazepine, phenytoin) that may alter metabolism of either component.
• Alcohol, which can exacerbate liver toxicity.