Gripomed (Pseudoephedrine Hydrochloride, Ibuprofen)

Gripomed is indicated for temporary relief of several common symptoms associated with colds, flu and minor musculoskeletal discomfort.

• Nasal congestion caused by colds, sinusitis or allergies.
• Headache or facial pain accompanying upper respiratory infections.
• Fever accompanying viral or bacterial infections.
• Minor aches such as sore throat, toothache or back pain.
• Muscle aches and joint discomfort related to mild strains.
• General discomfort or pain where an NSAID and decongestant are appropriate.

The safety profile of Gripomed reflects the combined actions of pseudoephedrine and ibuprofen, with side effects ranging from mild and frequent to rare but serious.

Common

• Dry mouth or throat irritation.
• Mild nausea or stomach upset.
• Dizziness or light‑headedness.
• Increased heart rate or mild palpitations.

Serious

• Severe allergic reaction such as rash, itching, swelling or difficulty breathing.
• High blood pressure or hypertensive crisis.
• Gastrointestinal bleeding or ulcer perforation.
• Liver enzyme elevation or hepatic injury.

When considering Gripomed, certain health conditions and patient factors require attention to minimize risk.

• Known hypersensitivity to pseudoephedrine, ibuprofen or any excipients.
• Existing hypertension, heart disease, or arrhythmias.
• History of stomach ulcers, gastrointestinal bleeding, or inflammatory bowel disease.
• Severe liver or kidney impairment.
• Use in pregnancy, breastfeeding or in children under the recommended age without medical advice.
• Concurrent use of other decongestants or NSAIDs may increase adverse effects.

Gripomed may interact with other medicines; some combinations should be avoided while others need careful monitoring.

Avoid

• Monoamine oxidase inhibitors (MAOIs) or recent MAOI therapy.
• Other sympathomimetic agents such as certain cough suppressants.
• Anticoagulants like warfarin, due to increased bleeding risk from ibuprofen.
• Selective serotonin reuptake inhibitors (SSRIs) that may raise bleeding risk.

Use with caution

• Antihypertensive drugs, as pseudoephedrine may reduce their effectiveness.
• Diuretics, which can increase the risk of low potassium levels.
• Lithium, because pseudoephedrine may raise lithium concentrations.
• Other NSAIDs or aspirin, which can enhance gastrointestinal side effects.