Grippal Complex (Pseudoephedrine Hydrochloride, Ibuprofen)

Grippal Complex is indicated for the symptomatic relief of several common cold and flu manifestations.

• Temporary relief of nasal congestion due to colds, sinusitis, or allergies.
• Reduction of fever associated with viral upper respiratory infections.
• Alleviation of mild to moderate headache or sinus pressure.
• Relief of body aches, sore throat discomfort, or general flu‑related pain.
• Supportive treatment of ear pressure or mild ear pain caused by congestion.

The safety profile of Grippal Complex reflects the combined actions of pseudoephedrine and ibuprofen. Most users experience mild, transient effects, while rare serious reactions may require medical attention.

Common

• Dry mouth or throat irritation.
• Mild nausea or stomach discomfort.
• Dizziness or light‑headedness, especially when standing quickly.
• Increased heart rate or mild palpitations.
• Headache that may be unrelated to the underlying illness.

Serious

• Severe allergic reactions such as rash, itching, swelling of the face, lips, or tongue.
• Gastrointestinal bleeding or ulcer symptoms (black stools, vomiting blood).
• High blood pressure spikes or chest pain.
• Signs of liver dysfunction (yellowing of skin or eyes).

Before using Grippal Complex, consider the following precautions to minimize risks and ensure appropriate use.

• Not recommended for individuals with uncontrolled hypertension, severe heart disease, or recent myocardial infarction.
• Avoid use in patients with a history of gastric ulcers, bleeding disorders, or chronic kidney disease.
• Do not exceed the recommended daily dose of ibuprofen, especially when combined with other NSAIDs.
• Use caution if you are pregnant, planning pregnancy, or breastfeeding; consult a healthcare professional.
• Avoid taking other decongestants or stimulant medications concurrently.
• Individuals with diabetes or thyroid disorders should monitor blood pressure while using pseudoephedrine.

Grippal Complex may interact with other medicines; awareness of these interactions helps prevent adverse effects.

Avoid

• Other NSAIDs (e.g., naproxen, aspirin) that increase risk of gastrointestinal bleeding.
• Monoamine oxidase inhibitors (MAOIs) or other sympathomimetic agents that can raise blood pressure.
• Certain antidepressants (e.g., SSRIs) that also elevate bleeding risk when combined with ibuprofen.

Use with caution

• Antihypertensive drugs, as pseudoephedrine may reduce their effectiveness.
• Diuretics or lithium, which can be affected by changes in sodium balance.
• Anticoagulants (e.g., warfarin) because ibuprofen may enhance anticoagulant effects.