Product image of Guanfacine 1mg Tablet supplied by GNH India

Guanfacine

Active Ingredient:
Guanfacine
Form:
Tablet
Brand:
Guanfacine
Origin:
USA

Guanfacine (Tablet) 1mg

Guanfacine, the active ingredient in Guanfacine, is an alpha-2 adrenergic agonist presented as a 1mg tablet for oral use. It is used to treat high blood pressure (hypertension) and attention deficit hyperactivity disorder (ADHD) in adults and children.

GNH India supplies Guanfacine as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Strength

1mg

Manufacturer / TM Owner

Slate Run Pharmaceuticals, LLC

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Indications & Clinical Uses

Guanfacine is an alpha-2 adrenergic agonist used to manage conditions related to the cardiovascular and central nervous systems.

  • Hypertension: Reduces blood pressure by relaxing blood vessels and decreasing heart rate.
  • Attention deficit hyperactivity disorder (ADHD): Improves focus and impulse control by affecting certain receptors in the brain.

How It Works

  • Guanfacine works by selectively stimulating alpha-2A adrenergic receptors in the brain, which reduces sympathetic outflow from the central nervous system. This action helps to lower blood pressure and improve attention and impulse control in individuals with ADHD.

Side Effects

Guanfacine may cause various side effects, ranging from common to serious or rare.

Common Side Effects

  • Drowsiness: May cause mild to moderate sleepiness.
  • Dry mouth: Reduced saliva production can lead to a dry mouth.
  • Dizziness: Some users may experience lightheadedness.
  • Fatigue: Mild tiredness or lack of energy.
  • Constipation: Slowed bowel movements.
  • Headache: Mild to moderate headaches.

Serious or Rare Side Effects

  • Slow heart rate: Can lead to bradycardia.
  • Fainting: May occur due to a drop in blood pressure.
  • Bipolar disorder: Can trigger episodes of mania or depression.
  • Liver damage: Rare but possible with prolonged use.

Precautions & Warnings

Guanfacine should be used with caution and under medical supervision.

  • Heart conditions: Use with caution in individuals with heart disease.
  • Low blood pressure: May exacerbate hypotension.
  • Liver disease: Dosage adjustments may be necessary.
  • Pregnancy: Consult a healthcare provider before use.
  • Breastfeeding: Use with caution and under medical advice.
  • Storage: Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Guanfacine may interact with other medications, potentially affecting its efficacy or increasing the risk of side effects.

Major Interactions (Avoid)

  • Blood pressure medications: May cause excessive lowering of blood pressure.
  • Antidepressants: Can enhance sedative effects.
  • Alcohol: Increases the risk of drowsiness and dizziness.

Moderate Interactions (Monitor Closely)

  • Other CNS depressants: May enhance sedative effects.
  • Diuretics: Can lead to electrolyte imbalances.
  • Beta-blockers: May cause additive effects on heart rate and blood pressure.

Frequently Asked Questions

Guanfacine is used to treat high blood pressure (hypertension) and attention deficit hyperactivity disorder (ADHD). It works by relaxing blood vessels and affecting certain receptors in the brain to improve focus and impulse control.

Guanfacine works by selectively stimulating alpha-2A adrenergic receptors in the brain. This action reduces sympathetic outflow from the central nervous system, which helps to lower blood pressure and improve attention and impulse control in individuals with ADHD.

The dosage of Guanfacine is determined by a healthcare provider based on the individual's condition, age, and response to treatment. It is important to follow the prescribed dosage and not to adjust it without medical advice.

Guanfacine is classified as a pregnancy category B drug, meaning it is generally considered safe during pregnancy. However, it should be used with caution and under medical supervision. For breastfeeding, consult a healthcare provider before use.

To order Guanfacine from GNH India, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams across international markets and will ask the buyer to confirm trade or institutional credentials. The team will reply with pricing, availability, shipping and the import paperwork.

Guanfacine is a non-stimulant medication used to treat ADHD, making it a suitable option for individuals who cannot tolerate stimulant medications. It works differently from stimulants like methylphenidate or amphetamines, focusing on improving attention and impulse control without the risk of abuse or dependence.

Guanfacine should be stored at room temperature, away from excess heat and moisture. Keep the medication in its original container, tightly closed, and out of reach of children. Avoid crushing or chewing the extended-release tablets.

Guanfacine is taken orally, usually once a day. The tablet should be swallowed whole with a small amount of water. It is important to take Guanfacine at the same time every day and to follow the prescribed dosage as directed by the healthcare provider.

The most serious risks associated with Guanfacine include slow heart rate, fainting, and liver damage. It is important to monitor for these side effects and to seek medical attention if they occur. Regular follow-ups with a healthcare provider are recommended.

Individuals with a history of heart conditions, low blood pressure, or liver disease should use Guanfacine with caution and under medical supervision. It is also important to inform the healthcare provider about all medications being taken to avoid potential interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

References

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