Gynoflor (Estriol, Lactobacillus Acidophilus, Lyophilized)

Gynoflor is used to address several gynecological conditions related to estrogen deficiency and vaginal microbiota imbalance. It is commonly prescribed for:

• Relief of vaginal dryness, itching, and burning associated with menopause.
• Management of mild atrophic vaginitis.
• Restoration of normal vaginal flora after antibiotic therapy.
• Adjunct therapy following treatment of bacterial vaginosis.
• Support of vaginal health in women using low‑dose estrogen therapy.

Side effects of Gynoflor are generally mild and related to local irritation, but rare serious reactions can occur.

Common

• Mild vaginal irritation or burning.
• Spotting or light vaginal bleeding.
• Increased vaginal discharge.
• Temporary itching or discomfort.

Serious

• Allergic reaction such as rash, swelling, or hives.
• Severe vaginal pain or ulceration.
• Persistent abnormal bleeding.
• Signs of infection like fever or foul odor.

Before using Gynoflor, consider the following precautions to ensure safe use:

• Confirm that you are not pregnant or planning pregnancy, as estrogen exposure may affect fetal development.
• Discuss any history of hormone‑dependent cancers (e.g., breast, ovarian) with your healthcare provider.
• Inform your clinician about existing vaginal infections or unexplained bleeding.
• Use the product only as directed; avoid prolonged use without medical supervision.
• Report any persistent irritation, bleeding, or allergic symptoms promptly.
• Store at room temperature away from moisture and direct sunlight.

Gynoflor may interact with other medications or products applied vaginally. Consider the following guidance:

Avoid

• Concurrent use of other estrogen‑containing vaginal products, which may increase systemic absorption.
• Vaginal antiseptics or spermicides that could disrupt the probiotic component.

Use with caution

• Systemic hormone therapies (e.g., oral contraceptives, hormone replacement) – monitor for additive estrogen effects.
• Antifungal or antibacterial vaginal treatments – coordinate timing to preserve probiotic viability.
• Immunosuppressive drugs – assess risk of infection when using probiotic preparations.