Product image of Gynosant (Fluconazole) supplied by GNH India

Gynosant

Active Ingredient:
Fluconazole
Origin:
EU

Gynosant (Fluconazole)

Gynosant is a prescription oral medication whose active ingredient is fluconazole, an azole antifungal. Marketed in the European Union, it is supplied as an oral dosage form; the exact strength is not specified in the public data. Fluconazole inhibits fungal cytochrome P450 enzymes, blocking ergosterol synthesis and disrupting cell membranes. It is listed under ATC code J02AX02 and is used to treat several types of candidiasis.

Manufacturer / TM Owner

Target Pharma Single Member Private Ltd

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Gynosant (fluconazole) is indicated for the treatment of fungal infections caused by susceptible Candida species and certain other fungi. It is commonly prescribed for infections of the genital, oral, esophageal, systemic, and central nervous system regions.

  • Vulvovaginal candidiasis (yeast infection of the vagina and vulva)
  • Oropharyngeal and esophageal candidiasis (thrush affecting mouth and esophagus)
  • Systemic candidiasis (bloodstream or organ infection)
  • Cryptococcal meningitis (fungal infection of the brain membranes)
  • Prophylaxis of candidiasis in immunocompromised patients

Side Effects

Side effects of Gynosant vary in frequency and severity. Common reactions are usually mild and reversible, while serious events are rare but require immediate medical attention.

Common

  • Nausea or vomiting
  • Abdominal discomfort or pain
  • Headache
  • Skin rash or pruritus
  • Diarrhea
  • Elevated liver enzymes (transaminases)

Serious

  • Severe liver injury or hepatitis
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Anaphylaxis or severe allergic reaction
  • Blood dyscrasias such as neutropenia or thrombocytopenia

Precautions & Warnings

Before starting Gynosant, certain health considerations should be reviewed to minimize risk.

  • Assess liver function; avoid use in patients with severe hepatic impairment.
  • Use caution in patients with renal dysfunction; dose adjustment may be required.
  • Review pregnancy and breastfeeding status; discuss potential risks with a healthcare professional.
  • Monitor for drug interactions, especially with medications metabolized by CYP450 enzymes.
  • Advise patients to report signs of severe skin reactions or liver problems promptly.
  • Consider baseline and periodic blood counts in patients receiving long‑term therapy.

Avoid Interactions

Fluconazole can affect the metabolism of many drugs; some combinations should be avoided, while others require careful monitoring.

Avoid

  • Cisapride, pimozide, and certain antiarrhythmics (risk of QT prolongation)
  • Rifampin or other strong CYP3A4 inducers (reduced fluconazole efficacy)
  • Certain statins (e.g., simvastatin, lovastatin) due to increased risk of myopathy
  • Oral anticoagulants such as warfarin (enhanced anticoagulant effect)

Use with caution

  • Phenytoin, carbamazepine, or phenobarbital (possible dose adjustments)
  • Cyclosporine or tacrolimus (monitor blood levels for toxicity)
  • Oral hypoglycemics (potential for increased hypoglycemia)
  • Benzodiazepines metabolized by CYP3A4 (possible increased sedation)

Frequently Asked Questions

Gynosant is used to treat infections caused by susceptible Candida species, including vulvovaginal candidiasis, oropharyngeal and esophageal thrush, systemic candidiasis, and cryptococcal meningitis.

Pregnancy safety has not been fully established for Gynosant. Women who are pregnant or planning pregnancy should discuss potential risks and benefits with their healthcare provider before using fluconazole.

Fluconazole inhibits the fungal enzyme 14α‑demethylase, a cytochrome P450 isoform, which blocks the synthesis of ergosterol, an essential component of the fungal cell membrane, leading to cell death.

Common side effects include nausea, abdominal pain, headache, skin rash, diarrhea, and temporary elevations in liver enzymes.

If a patient experiences signs of a serious reaction such as severe liver pain, jaundice, persistent vomiting, rash that spreads or blisters, or symptoms of an allergic reaction, they should discontinue the medication and seek immediate medical attention.

Yes. Fluconazole can interact with many OTC products, especially those containing antacids, certain antihistamines, or herbal supplements that affect CYP450 enzymes. Patients should review all medications and supplements with a pharmacist.

Patients with moderate to severe renal impairment may require dose adjustments of fluconazole. The prescribing clinician should evaluate kidney function before initiating therapy.

Fluconazole is sometimes prescribed prophylactically to prevent candidiasis in immunocompromised individuals, such as those undergoing chemotherapy or organ transplantation, under close medical supervision.

Baseline liver function tests and periodic monitoring are recommended, especially for long‑term use. Blood counts may also be monitored if there is concern for hematologic side effects.

Store Gynosant at room temperature, away from excess heat, moisture, and direct sunlight. Keep the medication out of reach of children and do not use it after the expiration date.

Yes, fluconazole is available as a generic medication in many markets, offering a comparable therapeutic effect to the branded product.

If a dose is missed, the patient should take it as soon as they remember unless it is close to the time for the next scheduled dose. They should not double the dose and should follow the prescribing clinician’s instructions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Fluconazole

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT