Product image of Haloxen (Haloperidol) supplied by GNH India

Haloxen

Active Ingredient:
Haloperidol
Origin:
EU

Haloxen (Haloperidol)

Haloxen is a prescription medication containing the antipsychotic agent haloperidol. It is supplied in oral dosage form, though specific strength may vary by market. Haloperidol belongs to the butyrophenone class and acts as a dopamine D2 receptor antagonist. Haloxen is marketed in the European Union and is used under medical supervision for certain psychiatric conditions. It is classified as a prescription‑only product and should be prescribed by a healthcare professional.

Manufacturer / TM Owner

Remedica Ltd

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Indications & Clinical Uses

Haloxen (haloperidol) is indicated for the management of certain psychotic disorders.

  • Schizophrenia, including maintenance therapy
  • Acute psychotic episodes, such as those associated with mania or severe stress
  • Short‑term control of agitation in hospitalized patients
  • Adjunctive treatment of Tourette syndrome when other therapies are insufficient
  • Management of delirium in intensive care settings when non‑pharmacologic measures are inadequate

Side Effects

Side effects of haloperidol may vary in frequency and severity.

Common

  • Drowsiness or sedation
  • Extrapyramidal symptoms such as tremor or rigidity
  • Dry mouth
  • Constipation
  • Blurred vision
  • Weight gain

Serious

  • Neuroleptic malignant syndrome
  • Tardive dyskinesia
  • Severe hypotension
  • Cardiac arrhythmias (QT prolongation)
  • Agranulocytosis
  • Seizures

Precautions & Warnings

When prescribing Haloxen, clinicians should consider several precautionary factors.

  • History of cardiovascular disease or prolonged QT interval
  • Pre‑existing movement disorders or Parkinsonian symptoms
  • Elderly patients, especially those with dementia‑related psychosis, due to increased mortality risk
  • Hepatic or renal impairment may require dose adjustment
  • Pregnancy and lactation status unknown; use only if benefit outweighs risk
  • Concomitant use with other central nervous system depressants

Avoid Interactions

Haloperidol can interact with other medications, affecting its efficacy or safety.

Avoid

  • Other antipsychotics or dopamine antagonists (increased risk of extrapyramidal effects)
  • Drugs that prolong QT interval (e.g., certain antiarrhythmics, macrolide antibiotics)
  • Strong CYP3A4 inhibitors such as ketoconazole (increased haloperidol levels)

Use with caution

  • CNS depressants including benzodiazepines or opioids (enhanced sedation)
  • Anticholinergic agents (may mask extrapyramidal symptoms)
  • CYP3A4 inducers like rifampin (reduced haloperidol levels)

Frequently Asked Questions

Haloxen is a prescription medication marketed in the European Union. Its active ingredient is haloperidol, a butyrophenone‑class antipsychotic.

Haloxen is taken orally. The specific dosage form and strength are determined by the prescribing physician and local regulations.

Haloxen is indicated for schizophrenia, acute psychotic episodes, short‑term agitation control, adjunctive treatment of Tourette syndrome, and management of delirium in intensive‑care settings.

Common adverse effects include drowsiness, extrapyramidal symptoms such as tremor or rigidity, dry mouth, constipation, blurred vision, and modest weight gain.

Serious reactions can include neuroleptic malignant syndrome, tardive dyskinesia, severe hypotension, cardiac arrhythmias (especially QT prolongation), agranulocytosis, and seizures.

Elderly patients, particularly those with dementia‑related psychosis, have an increased risk of mortality and should be monitored closely for cardiovascular and extrapyramidal effects.

Haloperidol blocks dopamine D2 receptors in the brain, decreasing dopaminergic neurotransmission that is thought to contribute to psychotic symptoms.

Medications that also prolong the QT interval, strong CYP3A4 inhibitors (e.g., ketoconazole), and other dopamine antagonists should generally be avoided.

The pregnancy and lactation categories for Haloxen are not established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant.

Regular monitoring may include ECG for QT interval, assessment of movement disorders, complete blood counts for agranulocytosis, and evaluation of metabolic parameters.

Haloxen (haloperidol) is a typical antipsychotic with strong dopamine D2 antagonism, whereas many newer agents are atypical antipsychotics with broader receptor profiles and often lower risk of extrapyramidal symptoms.

If a dose is missed, the patient should take it as soon as remembered unless it is near the time of the next scheduled dose. In that case, skip the missed dose and resume the regular dosing schedule. Always follow the prescribing clinician’s instructions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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