Product image of Handscrub (Chlorhexidine Gluconate) supplied by GNH India

Handscrub

Active Ingredient:
Chlorhexidine Gluconate
Origin:
EU

Handscrub (Chlorhexidine Gluconate)

Handscrub is an over‑the‑counter topical antiseptic that contains chlorhexidine gluconate as its active ingredient. It is formulated for hand antisepsis and skin disinfection, and is marketed in the European Union. The product works by disrupting bacterial cell membranes, providing broad‑spectrum antimicrobial activity for routine hygiene and clinical settings.

Manufacturer / TM Owner

Laboratórios Basi – Indústria Farmacêutica, S.A.

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Indications & Clinical Uses

Handscrub is intended for external use to reduce microbial contamination on the skin. It is commonly employed in healthcare and community environments where hand hygiene is critical.

  • Pre‑operative hand preparation for surgical staff
  • Routine hand hygiene in hospitals and clinics
  • Disinfection of skin before venipuncture or injection
  • Cleaning of hands after exposure to potentially contaminated surfaces
  • Use in food‑handling or laboratory settings where sterility is required

Side Effects

Side effects of Handscrub are generally mild and reversible, but rare serious reactions can occur.

Common

  • Mild skin irritation or redness at the application site
  • Transient itching or burning sensation
  • Dryness of the skin after repeated use
  • Minor rash or contact dermatitis

Serious

  • Severe allergic reaction (anaphylaxis) with swelling, difficulty breathing
  • Extensive skin necrosis or ulceration (very rare)
  • Persistent dermatitis requiring medical attention
  • Systemic toxicity if large amounts are absorbed (unlikely with normal use)

Precautions & Warnings

Before using Handscrub, consider the following safety measures to minimize risks.

  • Do not apply to broken, inflamed, or mucous membrane surfaces
  • Avoid contact with eyes; rinse immediately with water if exposure occurs
  • Discontinue use and seek medical advice if signs of allergic reaction develop
  • Keep out of reach of children; supervise use in pediatric settings
  • Store at room temperature, protected from direct sunlight and moisture
  • Use only as directed; excessive application does not increase efficacy

Avoid Interactions

Handscrub may interact with other topical agents or systemic medications. Review the following guidance.

Avoid

  • Concurrent use with other chlorhexidine‑containing products, which may increase irritation risk
  • Application over areas treated with topical antibiotics such as neomycin or bacitracin

Use with caution

  • Patients using systemic antihistamines or corticosteroids (may mask skin reactions)
  • Individuals with known hypersensitivity to chlorhexidine or related compounds
  • Use on skin pre‑treated with chemical peels or abrasive procedures (increased absorption)

Frequently Asked Questions

Handscrub contains chlorhexidine gluconate, which disrupts bacterial cell membranes, causing leakage of intracellular contents and leading to cell death.

No. Handscrub should not be applied to broken, inflamed, or mucous membrane surfaces because absorption may increase and irritation can worsen.

Handscrub is an OTC product, but it should be used under adult supervision. Avoid applying to children's facial skin and monitor for any signs of irritation.

Routine use as directed for hand hygiene is generally safe; however, excessive frequency may lead to dryness. Moisturizing after use can help maintain skin integrity.

Discontinue use immediately and consult a healthcare professional. A rash may indicate a mild allergic reaction or contact dermatitis.

Yes, Handscrub is commonly used for pre‑operative hand preparation of surgical staff and for disinfecting skin before invasive procedures.

No rinsing is required for routine hand antisepsis. If the product contacts eyes or a large area of broken skin, rinse thoroughly with water.

Concurrent use with other chlorhexidine‑based products should be avoided to reduce the risk of skin irritation.

Serious reactions may include swelling of the face or throat, difficulty breathing, hives, or a rapid heartbeat. Seek emergency medical care if these occur.

Store Handscrub at room temperature, away from direct sunlight and moisture, and keep the container tightly closed.

Yes, Handscrub is marketed in the EU and complies with regional regulations for over‑the‑counter antiseptic products.

Handscrub is intended for hand skin; gloves should be removed before application. After the product dries, gloves may be donned as per infection‑control protocols.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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