Product image of Hansepran 100mg (Clofazimine IP ) 100mg Capsule supplied by GNH India

Hansepran 100mg

Active Ingredient:
Clofazimine IP
Form:
Capsule
Brand:
Hansepran 100
Origin:
India

Hansepran 100mg (Clofazimine IP Capsule) 100mg

Hansepran 100mg is an oral antileprotic medication containing the active ingredient Clofazimine IP (100mg) in capsule form. Manufactured in India, this prescription drug belongs to the rimicompound class of medicines. It is primarily used in combination with other medications to treat leprosy and manage associated inflammatory complications.

Strength

100mg

Manufacturer / TM Owner

Sangrose Laboratories Pvt Ltd

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Indications & Clinical Uses

  • Hansepran 100mg is indicated for the treatment of multibacillary and paucibacillary leprosy (Hansen's disease) as part of a multi-drug therapy (MDT) regimen to prevent drug resistance. Additionally, it is used to treat and suppress erythema nodosum leprosum (ENL) reactions due to its dual antimicrobial and anti-inflammatory properties.

Side Effects

  • Common side effects of Hansepran 100mg include a reversible pink-to-brownish discoloration of the skin, hair, and bodily fluids such as sweat, sputum, urine, and tears. Other potential side effects include dry skin (ichthyosis), pruritus, abdominal pain, nausea, vomiting, diarrhea, and weight loss.

Precautions & Warnings

  • Hansepran 100mg is a Schedule H prescription drug in India and must be taken under strict medical supervision. It should be used with caution in patients with a history of gastrointestinal problems, liver disease, or depression related to skin discoloration. It is classified as Pregnancy Category C, meaning it should only be used during pregnancy if the potential benefits justify the risks to the fetus.

Avoid Interactions

  • Clofazimine in Hansepran 100mg may interact with other medications metabolized by the liver or drugs known to prolong the QT interval. Concomitant administration with rifampicin may reduce the absorption rate of clofazimine, potentially altering its therapeutic efficacy. Always consult a healthcare professional regarding all concurrent medications.

Frequently Asked Questions

Hansepran 100mg is primarily prescribed for the treatment of leprosy (Hansen's disease) and the management of erythema nodosum leprosum (ENL) inflammatory reactions.

Yes, the active ingredient Clofazimine commonly causes a pink-to-brownish discoloration of the skin, hair, and bodily secretions. This effect is usually reversible but may take several months to fade after stopping the medication.

Hansepran 100mg works by binding preferentially to mycobacterial DNA, which inhibits the growth and replication of Mycobacterium leprae, while also exerting anti-inflammatory actions to control leprosy reactions.

Hansepran 100mg is classified under Pregnancy Category C. It should only be used during pregnancy if prescribed by a doctor who has determined that the therapeutic benefits outweigh the potential risks to the fetus.

No, Hansepran 100mg is a Schedule H prescription drug in India and requires a valid prescription from a registered medical practitioner to be dispensed.

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Last updated:

References

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