Product image of Harmonet (Ethinylestradiol, Gestodene) supplied by GNH India

Harmonet

Active Ingredient:
Ethinylestradiol, Gestodene
Origin:
EU

Harmonet (Ethinylestradiol, Gestodene)

Harmonet is a combined oral contraceptive tablet containing the synthetic estrogen ethinylestradiol and the progestogen gestodene. It is supplied in tablet form and marketed in the European Union as a prescription‑only medication. The product works by suppressing ovulation and altering cervical mucus and the endometrial lining to prevent pregnancy. Harmonet is classified under ATC code G03AA07. It is intended for women seeking birth control and to help regulate menstrual cycles.

Manufacturer / TM Owner

Pfizer Spol. S R.O.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Harmonet is prescribed primarily for hormonal contraception and menstrual cycle management.

  • Prevention of pregnancy in women of reproductive age.
  • Regulation of irregular menstrual bleeding.
  • Reduction of dysmenorrhea associated with ovulatory cycles.
  • Management of acne that improves with estrogen‑progestogen therapy.
  • May be used as part of a post‑abortion or postpartum contraceptive plan under medical supervision.

Side Effects

Like other combined oral contraceptives, Harmonet can cause a range of side effects that vary in frequency and severity.

Common

  • Nausea or mild stomach upset.
  • Breast tenderness or enlargement.
  • Headache or mild migraine.
  • Spotting or breakthrough bleeding between periods.
  • Weight fluctuation or fluid retention.
  • Mood changes such as irritability.

Serious

  • Deep vein thrombosis or pulmonary embolism.
  • Stroke or transient ischemic attack.
  • Severe hypertension.
  • Liver dysfunction or jaundice.
  • Allergic reactions with rash or swelling.

Precautions & Warnings

Before starting Harmonet, healthcare providers assess several health factors to ensure safe use.

  • History of thromboembolic disorders, stroke, or myocardial infarction.
  • Uncontrolled hypertension or diabetes with vascular complications.
  • Current or past smoking in women over 35 years of age.
  • Known liver disease or severe gallbladder disease.
  • Pregnancy or suspected pregnancy (category X).
  • Breast cancer or estrogen‑dependent tumors.
  • Migraine with aura.

Avoid Interactions

Harmonet may interact with other medicines, affecting its effectiveness or increasing health risks.

Avoid

  • Strong enzyme inducers such as rifampicin, carbamazepine, phenytoin, and St John’s wort.
  • Anticoagulants like warfarin, which may have reduced efficacy.
  • Certain antiviral agents (e.g., protease inhibitors) that alter hormone metabolism.

Use with caution

  • Antidepressants (SSRIs) that can increase bleeding risk.
  • Antifungal agents (ketoconazole, itraconazole) that may raise hormone levels.
  • Diuretics or antihypertensives that may affect blood pressure control.

Frequently Asked Questions

Harmonet delivers ethinylestradiol and gestodene, which suppress the hypothalamic‑pituitary‑ovarian axis, lowering LH and FSH secretion, thereby inhibiting ovulation and producing cervical mucus and endometrial changes that prevent fertilization and implantation.

If a tablet is missed, the usual recommendation is to take the missed tablet as soon as remembered and continue with the regular schedule, using backup contraception for the next 7 days. Specific guidance should be obtained from a healthcare professional.

Harmonet contains an estrogen component that can improve acne in some women, but it is not primarily indicated for acne treatment. Any benefit is considered a secondary effect and should be discussed with a prescriber.

Smoking, especially in women over 35, increases the risk of cardiovascular events with combined oral contraceptives. Harmonet is generally contraindicated for smokers in this age group and should be used with caution in younger smokers.

Harmonet may be started postpartum once bleeding has ceased and the woman is not breastfeeding, typically after 6 weeks. If breastfeeding, a progestogen‑only method is usually preferred.

Most antibiotics do not affect the efficacy of combined oral contraceptives. However, enzyme‑inducing antibiotics such as rifampicin can reduce hormone levels and should be avoided or supplemented with additional contraception.

Some users report mild weight fluctuation or fluid retention, which is listed as a common side effect. Significant weight gain is not a typical effect of Harmonet.

Harmonet is usually packaged in a 21‑day active tablet regimen followed by a hormone‑free interval. Some formulations include placebo tablets to maintain a 28‑day cycle, but the specific packaging should be confirmed on the product label.

If pregnancy is confirmed, Harmonet should be discontinued immediately. The woman should seek prenatal care and discuss any potential risks with her healthcare provider.

There are no specific dietary restrictions, but excessive alcohol consumption can increase the risk of liver problems and should be avoided. A balanced diet supports overall health while using hormonal contraception.

Migraine with aura is a contraindication for combined estrogen‑progestogen contraceptives because of an increased risk of stroke. Women with this history should consider alternative non‑estrogen methods.

Store Harmonet tablets at room temperature, away from moisture and heat, and keep them out of reach of children. Do not use tablets that are discolored or past the expiration date.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ethinylestradiol, Gestodene

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT