Hascovir Control Max (Aciclovir)

Hascovir Control Max is indicated for the treatment of infections caused by herpes viruses, where oral antiviral therapy is appropriate.

• Primary genital herpes (HSV‑1 and HSV‑2) infections.
• Oral herpes (cold sores) caused by HSV‑1.
• Shingles (herpes zoster) resulting from varicella‑zoster virus reactivation.
• Suppressive therapy to reduce recurrence of genital herpes.
• Treatment of varicella (chickenpox) in immunocompromised patients when oral therapy is preferred.
• Post‑exposure prophylaxis for HSV exposure in high‑risk individuals.

Side effects reported with oral aciclovir, the active component of Hascovir Control Max, are generally mild but can vary among patients.

Common

• Nausea or upset stomach.
• Headache.
• Dizziness.
• Mild skin rash.

Serious

• Kidney function impairment or acute renal failure.
• Severe allergic reactions such as anaphylaxis.
• Blood cell abnormalities (e.g., neutropenia, thrombocytopenia).
• Confusion or hallucinations, especially in elderly patients.

Before starting Hascovir Control Max, certain precautions should be considered to ensure safe use and to minimize risk of complications.

• Assess kidney function; dose adjustment may be needed in renal impairment.
• Review patient’s medical history for immunosuppression or severe systemic disease.
• Use with caution in elderly patients due to higher risk of renal side effects.
• Avoid use during pregnancy or breastfeeding unless clearly indicated by a healthcare professional.
• Monitor for signs of allergic reaction, especially after the first dose.
• Ensure adequate hydration to support renal clearance.

Aciclovir can interact with other medicines, which may affect its effectiveness or increase the risk of adverse effects.

Avoid

• Concomitant use with nephrotoxic agents such as aminoglycoside antibiotics (e.g., gentamicin) or high‑dose NSAIDs, which may increase the risk of kidney injury.
• Co‑administration with probenecid, a drug that reduces renal clearance of aciclovir, potentially leading to elevated plasma concentrations.

Use with caution

• Combining aciclovir with other antiviral medications (e.g., valacyclovir or famciclovir) may increase the likelihood of toxicity and should be monitored.
• Use with caution in patients receiving cimetidine, as it can raise aciclovir levels by reducing renal excretion.
• Patients on immunosuppressive therapy should be closely observed, since altered immune function can affect infection severity and drug response.