Hastina 21+7 (Drospirenone, Ethinylestradiol | Lactose Anhydrous)

Hastina 21+7 is indicated for women who seek reliable hormonal contraception.

• Prevention of pregnancy in women of reproductive age.
• Use as part of a regular 21‑day active/7‑day placebo cycle.
• May be prescribed for menstrual cycle regulation when clinically appropriate.
• Can be considered for management of acne related to androgen excess in some patients.
• Provides contraceptive protection immediately after the first tablet when a backup method is not required after the first 7 days.

Like other combined oral contraceptives, Hastina 21+7 may cause a range of side effects, most of which are mild and transient.

Common

• Nausea or mild stomach upset, often occurring during the first cycle.
• Headache or mild migraine, which may improve after continued use.
• Breast tenderness or enlargement, typically resolving after several weeks.
• Spotting or breakthrough bleeding between periods, especially during the initial weeks.

Serious

• Signs of venous thromboembolism such as leg pain, swelling, redness, or sudden shortness of breath, which require immediate medical attention.
• Severe allergic reaction including rash, itching, swelling of the face, lips, tongue, or throat, indicating possible anaphylaxis.

Before prescribing Hastina 21+7, clinicians evaluate several health factors to ensure safe use.

• History of blood clotting disorders, stroke, or myocardial infarction.
• Current or past diagnosis of hormone‑dependent cancers such as breast or endometrial cancer.
• Uncontrolled hypertension or significant cardiovascular disease.
• Smoking in women over 35 years of age.
• Liver disease that impairs hormone metabolism.
• Pregnancy or suspected pregnancy.
• Known allergy to drospirenone, ethinylestradiol, or lactose.

Hastina 21+7 can interact with other medicines, affecting its effectiveness or safety.

Avoid

• Anticoagulants such as warfarin, which may have reduced efficacy.
• Enzyme‑inducing anticonvulsants (e.g., carbamazepine, phenytoin) that lower hormone levels.
• Certain antibiotics like rifampin that increase hormone metabolism.
• St. John’s wort, a herbal inducer of hepatic enzymes.
• HIV protease inhibitors that may increase estrogen levels.

Use with caution

• Antifungal agents (e.g., ketoconazole) that can raise hormone concentrations.
• Selective serotonin reuptake inhibitors (SSRIs) that may slightly increase clot risk.
• Diuretics that may affect potassium balance when combined with drospirenone.