Product image of Havrix Junior (Algeldrate, Hepatitis A Virus Antigen (Inactivated)) supplied by GNH India

Havrix Junior

Active Ingredient:
Algeldrate, Hepatitis A Virus Antigen (Inactivated)
Origin:
EU

Havrix Junior (Algeldrate, Hepatitis A Virus Antigen (Inactivated))

Havrix Junior is an injectable solution containing the inactivated hepatitis A virus antigen (algeldrate) formulated for intramuscular use. It is a prescription vaccine approved in the European Union for the prevention of hepatitis A infection in children. The product delivers a standardized antigen dose to stimulate active immunity without containing live virus.

Manufacturer / TM Owner

Glaxosmithkline Biologicals S.A.

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Indications & Clinical Uses

Havrix Junior is indicated for active immunisation against hepatitis A in pediatric populations. It is used according to national immunisation schedules to reduce the risk of infection and associated liver disease.

  • Primary vaccination of children aged 1 year and older
  • Completion of a two‑dose series for long‑term protection
  • Travel to regions with high hepatitis A endemicity
  • Outbreak control in schools or community settings
  • Use in children with chronic liver disease when recommended by a healthcare professional

Side Effects

Side effects of Havrix Junior are generally mild and transient, reflecting the body’s immune response to the vaccine. Serious adverse events are rare but should be monitored.

Common

  • Pain, redness, or swelling at the injection site
  • Low‑grade fever within 24‑48 hours
  • Mild headache or fatigue
  • Transient muscle aches

Serious

  • Severe allergic reaction (anaphylaxis)
  • High fever persisting more than 48 hours
  • Neurological symptoms such as seizures (very rare)

Precautions & Warnings

Before administering Havrix Junior, certain precautions should be considered to ensure safe use.

  • Verify that the child has no known severe allergy to any vaccine component
  • Defer vaccination in the presence of moderate or severe acute illness
  • Assess risk versus benefit in children with immunodeficiency conditions
  • Counsel caregivers about the possibility of mild fever or injection‑site reactions
  • Document any previous adverse reaction to hepatitis A vaccines
  • Follow local guidelines for the timing of the second dose

Avoid Interactions

Havrix Junior may interact with other medical products, influencing its safety or effectiveness.

Avoid

  • Concurrent administration of live viral vaccines within 4 weeks
  • Use of immunoglobulin products that could neutralise the vaccine antigen
  • Administration of blood products immediately before or after vaccination

Use with caution

  • Concurrent receipt of other inactivated vaccines (spacing may be recommended)
  • Use in children receiving immunosuppressive therapy
  • Co‑administration with antipyretics may mask fever response
  • Vaccination in children on chronic corticosteroid therapy

Frequently Asked Questions

The active ingredient is an inactivated hepatitis A virus antigen, also known as algeldrate, which stimulates the immune system to produce protective antibodies.

Havrix Junior is approved for use in children aged 1 year and older, following the recommended immunisation schedule.

A typical schedule consists of two doses administered several months apart; the exact interval depends on national guidelines.

It can be co‑administered with other inactivated vaccines, but live viral vaccines should be spaced at least four weeks apart to avoid interference.

Common reactions include pain, redness, or swelling at the injection site, low‑grade fever, mild headache, fatigue, and transient muscle aches.

Serious adverse events are rare but may include severe allergic reactions (anaphylaxis) and, very rarely, neurological symptoms such as seizures.

Vaccination is generally deferred in children with moderate or severe acute illness until they recover.

Vaccination may be recommended for children with chronic liver disease, but it should be evaluated by a healthcare professional based on individual risk.

Yes, immunoglobulin products given close to vaccination can neutralise the antigen and reduce the vaccine’s effectiveness; timing should be managed carefully.

A low‑grade fever is common and usually resolves within 48 hours; parents can use age‑appropriate antipyretics and should contact a healthcare provider if the fever persists or is high.

No, Havrix Junior is a prescription‑only vaccine and must be administered by a qualified healthcare professional.

The vaccine should be stored in a refrigerator between 2 °C and 8 °C and protected from light; it must not be frozen.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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