Hayfever & Allergy Relief (Cetirizine Dihydrochloride)

Hayfever & Allergy Relief is indicated for the symptomatic treatment of several common allergic conditions.

• Relief of nasal congestion, sneezing and itching associated with hay fever (allergic rhinitis).
• Reduction of skin itching, hives and swelling in urticaria.
• Alleviation of eye irritation, redness and tearing caused by allergic conjunctivitis.
• Management of other seasonal allergy symptoms such as runny nose and itchy throat.
• Support for occasional allergic reactions to insect bites or mild food allergens when symptoms are limited to histamine‑mediated itching.

The safety profile of cetirizine dihydrochloride includes both frequent, mild reactions and rare, more serious events.

Common

• Drowsiness or mild fatigue
• Dry mouth
• Headache
• Nausea
• Dizziness
• Abdominal pain
• Diarrhea
• Blurred vision

Serious

• Severe skin rash or Stevens‑Johnson syndrome
• Swelling of the face, lips or tongue (angioedema)
• Rapid or irregular heartbeat
• Difficulty breathing or bronchospasm
• Anaphylaxis
• Liver enzyme elevation
• Seizures

Before using Hayfever & Allergy Relief, certain precautionary measures should be considered to ensure safe and effective use.

• Assess kidney function, as cetirizine is primarily excreted renally.
• Use with caution in patients with a history of severe allergic reactions or asthma.
• Avoid operating machinery or driving if drowsiness occurs.
• Discuss use with a healthcare professional if pregnant, planning pregnancy, or breastfeeding.
• Review all concurrent medications for potential interactions.
• Monitor for signs of skin rash or swelling during initial treatment.
• Do not exceed the recommended daily dose.

Cetirizine can interact with other substances; awareness of these interactions helps minimize adverse effects.

Avoid

• Alcohol or other central nervous system depressants that may increase drowsiness.
• Strong CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) that could raise cetirizine levels.
• Other antihistamines or sedating allergy medications, which may compound sedation.
• Ritonavir, a potent CYP3A4 inhibitor, which may significantly increase cetirizine plasma concentrations.

Use with caution

• Theophylline, as it may reduce antihistamine effectiveness.
• Phenobarbital or carbamazepine, which can increase cetirizine clearance.
• Certain antidepressants (e.g., fluoxetine) that may affect metabolism.
• St. John’s wort, which may induce metabolic enzymes.