Product image of Hc45 (Hydrocortisone Acetate) supplied by GNH India

Hc45

Active Ingredient:
Hydrocortisone Acetate
Origin:
EU

Hc45 (Hydrocortisone Acetate)

Hc45 is a topical product containing the corticosteroid active ingredient Hydrocortisone Acetate. The formulation is intended for skin application, though specific strength and dosage form are not disclosed. It is marketed in the European Union and belongs to the class of topical corticosteroids used to manage inflammatory skin conditions.

Manufacturer / TM Owner

Karo Pharma Ab

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Indications & Clinical Uses

Hc45 is applied to the skin to alleviate symptoms of various inflammatory dermatologic disorders. It is commonly employed by healthcare professionals for short‑term management of conditions that respond to corticosteroid therapy.

  • Treatment of mild to moderate dermatitis
  • Relief of eczema flare‑ups
  • Management of localized inflammatory skin lesions
  • Adjunct therapy for psoriasis plaques
  • Soothing of allergic skin reactions

Side Effects

Topical Hydrocortisone Acetate can cause a range of skin‑related reactions, most of which are mild and reversible. Serious adverse events are uncommon but may require medical attention.

Common

  • Mild burning or stinging at the application site
  • Transient itching or redness
  • Slight skin thinning with prolonged use

Serious

  • Development of secondary bacterial, fungal, or viral skin infections
  • Allergic contact dermatitis manifesting as rash or swelling
  • Systemic absorption leading to adrenal suppression (rare with extensive use)

Precautions & Warnings

Before using Hc45, consider the following safety measures to minimize risks and ensure appropriate use.

  • Avoid application on broken, infected, or ulcerated skin unless directed by a clinician
  • Limit use to the prescribed area and duration to reduce skin atrophy
  • Do not cover treated skin with occlusive dressings unless advised
  • Consult a healthcare professional before use in children or the elderly
  • Discontinue and seek medical advice if signs of infection appear
  • Review pregnancy and lactation status with a provider, as safety data are limited

Avoid Interactions

Hc45 may interact with other topical agents or systemic medications that affect corticosteroid activity. Consider these interactions when planning treatment.

Avoid

  • Concurrent use of other potent topical steroids on the same area
  • Application of topical antibiotics or antifungals that may irritate the skin
  • Use with systemic immunosuppressants without monitoring

Use with caution

  • Combining with non‑steroidal anti‑inflammatory creams
  • Applying over large body surface areas in patients with diabetes
  • Use in conjunction with photosensitizing agents
  • Concurrent use of oral corticosteroids, which may increase systemic effects

Frequently Asked Questions

Hc45 is indicated for mild to moderate dermatitis, eczema, localized psoriasis plaques, and other inflammatory skin conditions that respond to topical corticosteroids.

Apply a thin layer to the affected area once or twice daily, as directed by a healthcare professional, and gently rub it in until the skin no longer feels oily.

Use in children should be under medical supervision, with attention to lower potency, limited surface area, and shorter treatment duration.

Common side effects include mild burning, stinging, transient itching, and slight skin thinning when used for extended periods.

Discontinue use and contact a healthcare provider if you notice worsening redness, swelling, signs of infection, or an allergic rash.

Avoid layering with other potent topical steroids or irritant creams unless a clinician advises; some moisturizers may be used after the medication has absorbed.

Systemic effects are rare with topical use, but extensive application over large body areas or prolonged use can increase the risk of adrenal suppression.

Occlusive dressings should not be used unless specifically recommended, as they can enhance absorption and raise the likelihood of side effects.

Rinse the area thoroughly with water and seek medical attention promptly, as the product is not intended for ocular or mucosal use.

The regulatory status varies by country; in many EU markets, Hydrocortisone Acetate topical preparations may require a prescription.

Typical treatment courses last from a few days up to two weeks; longer use should be monitored by a healthcare professional to prevent skin atrophy.

Store at room temperature, away from excess heat and moisture, and keep the container tightly closed when not in use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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