Product image of Hedrin (Dimeticone) supplied by GNH India

Hedrin

Active Ingredient:
Dimeticone
Origin:
EU

Hedrin (Dimeticone)

Hedrin is an over‑the‑counter pediculicide lotion containing 4% w/v dimeticone, a silicone‑based compound. It is formulated for cutaneous application to treat head‑lice infestation (pediculosis capitis) and is marketed in the European Union. The product works by physically coating lice, blocking their respiratory spiracles, and causing suffocation without relying on chemical insecticides.

Manufacturer / TM Owner

Thornton & Ross Ltd

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Indications & Clinical Uses

Hedrin is indicated for the topical treatment of head lice infestations in individuals of all ages. It is applied to dry hair and scalp, left in place for the recommended time, then rinsed off.

  • Effective against live lice and newly hatched nymphs.
  • Suitable for use on children older than 6 months and adults.
  • Can be used as part of an integrated lice‑control program that includes combing.
  • Does not contain neurotoxic insecticides, reducing risk of resistance.
  • Provides a non‑chemical alternative for families seeking silicone‑based options.

Side Effects

Side effects reported with Hedrin are generally mild and related to the topical nature of the product.

Common

  • Mild scalp irritation or itching.
  • Transient redness at the application site.
  • Dryness or flaking of hair.
  • Temporary tingling sensation.

Serious

  • Allergic contact dermatitis (rash, swelling, blistering).
  • Severe itching or swelling requiring medical evaluation.
  • Rare systemic reactions such as urticaria.
  • Persistent irritation beyond 24 hours.
  • Secondary infection from scratching affected areas.

Precautions & Warnings

Before using Hedrin, consider the following safety measures to minimize adverse reactions.

  • Perform a patch test on a small skin area 24 hours before full application.
  • Avoid use on broken, inflamed, or sunburned skin.
  • Do not apply to eyes, mucous membranes, or open wounds.
  • Keep the product out of reach of children; store at room temperature.
  • If pregnancy or breastfeeding status is unknown, consult a healthcare professional before use.
  • Discontinue use and seek medical advice if signs of an allergic reaction develop.

Avoid Interactions

Hedrin’s silicone base has limited potential for drug interactions, but certain substances may affect its performance.

Avoid

  • Applying other topical medicated shampoos or hair treatments immediately before or after Hedrin.
  • Use on hair that has been chemically treated (e.g., bleach, perm) without thorough rinsing.

Use with caution

  • Concurrent use of scalp moisturizers or oils that may create a barrier over the product.
  • Application on hair containing heavy styling products that could reduce coating efficacy.
  • Use in combination with other lice‑control products; follow timing recommendations to avoid overlapping exposure.

Frequently Asked Questions

Hedrin contains dimeticone, a silicone‑based compound that physically coats lice, blocking their respiratory spiracles and causing suffocation without chemical toxicity.

Yes, Hedrin is formulated for use on children older than six months, but a patch test is recommended before full application.

The product label advises applying Hedrin to dry hair, leaving it on for the specified time (usually 10–15 minutes) before thorough rinsing.

Dimeticone can coat newly hatched nymphs and some nits, but mechanical removal with a fine‑toothed comb is recommended to eliminate all eggs.

A second application is often suggested 7–10 days after the first to target any lice that may have hatched after the initial treatment.

Discontinue use, rinse the scalp with water, and if irritation persists, seek advice from a healthcare professional.

It can be used, but it is advisable to rinse out any hair dyes, bleaches, or perms before applying Hedrin to ensure proper coating.

The pregnancy safety category is unknown; women who are pregnant or breastfeeding should consult a healthcare provider before use.

Unlike neurotoxic insecticides, Hedrin’s silicone base works mechanically, reducing the risk of resistance and chemical exposure.

Combining products is not recommended without professional guidance, as overlapping treatments may increase skin irritation.

Store Hedrin at room temperature, away from direct sunlight and out of reach of children.

No, Hedrin is an over‑the‑counter (OTC) product and does not require a prescription.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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