Product image of Helixor M (Liquid Extract From Viscum Album Subsp. Album Var Malus Domestica (1:20), Extraction Solvents: Water) supplied by GNH India

Helixor M

Active Ingredient:
Liquid Extract From Viscum Album Subsp. Album Var Malus Domestica (1:20), Extraction Solvents: Water
Origin:
EU

Helixor M (Liquid Extract From Viscum Album Subsp. Album Var Malus Domestica (1:20), Extraction Solvents: Water)

Helixor M is an injectable solution that contains a liquid extract of Viscum album subsp. album var. Malus domestica (1:20), prepared with water as the extraction solvent. Classified as a herbal medicinal product, it is administered subcutaneously for use in oncology care. The product is marketed in the European Union and is intended to be used under the supervision of a healthcare professional as part of a cancer treatment plan.

Manufacturer / TM Owner

Helixor Heilmittel Gmbh

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Indications & Clinical Uses

Helixor M is used as an adjunct in oncology settings, where it is administered alongside conventional cancer therapies to support the immune system and to provide supportive care.

  • Adjunct therapy for solid tumors such as breast, lung, and colorectal cancer.
  • Supportive care to improve quality of life during chemotherapy or radiotherapy.
  • Immunomodulatory support in patients with hematologic malignancies.
  • Part of integrative oncology protocols aimed at reducing treatment‑related fatigue.
  • Investigational use in clinical studies evaluating tumor‑associated immune response.

Side Effects

Side‑effect reporting for Helixor M reflects its herbal nature and subcutaneous administration, with most reactions being mild, generally self‑limiting, and reversible.

Common

  • Local redness, swelling, or mild pain at the injection site.
  • Low‑grade fever or transient chills.
  • Mild fatigue or headache.

Serious

  • Severe allergic reaction (anaphylaxis) with breathing difficulty.
  • Persistent high fever (>38.5 °C) lasting more than 24 hours.
  • Unexplained bleeding, bruising, or sudden drop in blood pressure.

Precautions & Warnings

When prescribing Helixor M, clinicians should evaluate patient history and monitor for specific conditions that may increase the risk of adverse events or reduce therapeutic benefit.

  • Avoid use in patients with known hypersensitivity to Viscum album extracts.
  • Exercise caution in individuals with autoimmune disorders or immunosuppression.
  • Monitor blood counts regularly during therapy.
  • Assess liver and kidney function before initiation and periodically thereafter.
  • Discuss potential effects with pregnant or breastfeeding women; safety data are limited.
  • Consider dose adjustments in elderly patients with comorbidities.

Avoid Interactions

Helixor M may interact with other medications or biologic agents; awareness of these possibilities helps prevent reduced efficacy or heightened toxicity.

Avoid

  • Concurrent use with immunosuppressive chemotherapy agents that may blunt the intended immunomodulatory effect.
  • Combination with other herbal preparations containing mistletoe extracts, which could increase toxicity.

Use with caution

  • Anticoagulants or antiplatelet drugs, due to potential for increased bleeding risk.
  • Cytokine therapies (e.g., interferon) that may amplify immune activation.
  • Vaccinations, as immune modulation could affect vaccine response.
  • Hormonal therapies, pending clinical judgment.

Frequently Asked Questions

Helixor M contains Viscum album extract, which is thought to modulate the immune response and exhibit cytotoxic activity against tumor cells, thereby supporting conventional anticancer therapies.

Helixor M is supplied as an injectable solution that is given by subcutaneous injection, usually in a clinical setting under medical supervision.

It is most frequently used alongside standard treatment for solid tumors such as breast, lung, colorectal, and prostate cancers, as well as for certain hematologic malignancies.

Commonly reported effects include mild injection‑site reactions, low‑grade fever, transient chills, mild fatigue, and occasional headache.

Safety data for use in pregnancy or lactation are limited; clinicians should weigh potential risks and discuss uncertainties with the patient before prescribing.

Regular monitoring of blood counts, liver and kidney function, and observation for any allergic reactions or unexpected bleeding is recommended during therapy.

Potential interactions include immunosuppressive chemotherapy agents, other mistletoe‑based herbal products, anticoagulants, cytokine therapies, and vaccines, which may require caution or avoidance.

Clinicians should assess for hypersensitivity to mistletoe extracts, review autoimmune or immunosuppressive conditions, evaluate organ function, and consider patient age and comorbidities.

Helixor M is classified as a prescription‑only medication and must be prescribed by a qualified healthcare professional.

Helixor M is a specific Viscum album subsp. album var. Malus domestica extract prepared at a 1:20 ratio with water, and it is marketed in the EU as a subcutaneous injectable formulation.

Several observational studies and phase II trials have reported immunomodulatory effects and improved quality‑of‑life measures when Helixor M is used as an adjunct to standard cancer therapies.

Helixor M is often administered alongside chemotherapy; however, clinicians should monitor for possible attenuation of immunosuppressive effects and adjust treatment plans accordingly.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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