Hemafer Fol (Folic Acid, Ferric Hydroxide Polymaltose Complex)

Hemafer Fol is indicated for conditions where increased folate or iron intake is needed to support normal blood formation and cellular function.

• Management of folate deficiency identified by low serum folate levels.
• Treatment of iron deficiency anemia when oral iron supplementation is appropriate.
• Prevention of anemia during pregnancy in women with increased nutritional requirements.
• Support for individuals on restricted diets that may lack adequate folate or iron.
• Adjunct therapy in chronic conditions associated with increased red‑cell turnover.
• Use in patients undergoing bariatric surgery who may have reduced absorption of folate and iron.

The safety profile of Hemafer Fol reflects the known effects of its individual components, folic acid and iron, when taken at typical supplemental doses.

Common

• Mild gastrointestinal discomfort such as nausea or abdominal bloating.
• Transient darkening of stools due to iron content.
• Headache or mild dizziness, especially when initiating therapy.
• Metallic taste in the mouth after ingestion.
• Occasional constipation or loose stools, depending on individual tolerance.

Serious

• Allergic reactions including rash, itching, or swelling of the face and throat.
• Severe abdominal pain or persistent vomiting indicating possible intolerance.
• Signs of iron overload such as joint pain, fatigue, or abnormal liver function tests.
• Unexplained fever or chills that may suggest infection.

When using Hemafer Fol, certain precautions should be observed to minimize risk and ensure appropriate use in specific populations.

• Assess baseline folate and iron status before initiating supplementation.
• Use with caution in individuals with known hypersensitivity to folic acid or iron compounds.
• Avoid excessive dosing, as high folic acid may mask vitamin B12 deficiency symptoms.
• Monitor for signs of iron overload in patients with hereditary hemochromatosis or chronic liver disease.
• Pregnant or breastfeeding women should consult a healthcare professional prior to use.
• Children under the recommended age should not be given the product without medical advice.

Hemafer Fol may interact with certain medications or nutrients; awareness of these interactions helps maintain therapeutic effectiveness and safety.

Avoid

• Concurrent use of high‑dose iron chelators, which can reduce iron absorption from the supplement.
• Antacids containing aluminum or magnesium taken within two hours, as they may impair iron uptake.

Use with caution

• Levothyroxine, because iron can decrease its absorption; separate dosing by at least four hours.
• Antibiotics such as tetracyclines or quinolones, which may form complexes with iron and reduce efficacy.
• Methotrexate therapy, where folic acid supplementation may be recommended but dosage should be coordinated with the prescribing clinician.