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Hemafer

Active Ingredient:
Iron (Iii) Ion
Origin:
EU

Hemafer (Iron (Iii) Ion)

Hemafer is an oral iron supplement containing iron (III) ion as its active ingredient; it is marketed in the European Union as an over‑the‑counter product. The preparation provides elemental iron for incorporation into hemoglobin and myoglobin, supporting normal erythropoiesis. Formulation details such as strength and dosage form are not specified in the available data.

Manufacturer / TM Owner

Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A.

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Indications & Clinical Uses

Hemafer is indicated for the prevention and treatment of iron deficiency in various clinical situations.

  • Management of iron‑deficiency anemia diagnosed by laboratory testing.
  • Supplementation in individuals with dietary iron insufficiency.
  • Support of maternal iron requirements during pregnancy.
  • Prevention of iron deficiency in children, adolescents, or other at‑risk groups.
  • Adjunct therapy for patients with chronic blood loss or malabsorption conditions.
  • Use in patients undergoing bariatric surgery or other procedures that limit iron absorption.

Side Effects

Oral iron supplementation may be associated with a range of gastrointestinal and systemic effects, most of which are mild and transient.

Common

  • Nausea or mild stomach upset.
  • Constipation or soft stools.
  • Darkening of the feces.
  • Metallic taste in the mouth.
  • Abdominal cramping or gas.

Serious

  • Severe allergic reaction (rash, swelling, difficulty breathing).
  • Signs of iron overload (joint pain, fatigue, abdominal pain).
  • Persistent vomiting or inability to retain oral medication.
  • Unexplained dark urine or hematuria.
  • Sudden onset of severe abdominal pain.

Precautions & Warnings

When considering Hemafer, several precautionary measures should be observed to ensure safe and effective use.

  • Confirm iron deficiency with appropriate laboratory tests before initiating therapy.
  • Use the lowest effective dose and monitor hemoglobin and ferritin levels periodically.
  • Avoid use in individuals with known hypersensitivity to iron preparations.
  • Caution in patients with hereditary hemochromatosis, thalassemia, or other iron‑loading disorders.
  • Consider potential gastrointestinal irritation; take with food if tolerated.
  • Pregnant or breastfeeding women should consult a healthcare professional before use.
  • Keep out of reach of children to prevent accidental overdose.

Avoid Interactions

Iron ions can affect the absorption or activity of several other medications and nutrients.

Avoid

  • Tetracycline antibiotics (e.g., doxycycline, minocycline) taken concurrently.
  • Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin) taken at the same time.
  • Levothyroxine or other thyroid hormone replacements.

Use with caution

  • Antacids containing aluminum, magnesium, or calcium.
  • Proton pump inhibitors or H2‑blockers that reduce gastric acidity.
  • Certain bisphosphonates (e.g., alendronate) if taken orally.
  • Vitamin C supplements, which may increase iron absorption and risk of gastrointestinal upset.

Frequently Asked Questions

Hemafer contains iron (III) ion, which provides elemental iron needed for hemoglobin and myoglobin synthesis.

Yes, Hemafer is classified as an over‑the‑counter (OTC) product in the European Union.

It is used to treat iron‑deficiency anemia, supplement dietary iron insufficiency, support iron needs during pregnancy, and prevent deficiency in at‑risk populations.

Iron is best absorbed on an empty stomach, but if gastrointestinal upset occurs, it can be taken with a small amount of food; avoid concurrent intake of calcium‑rich foods or antacids.

Pregnant women may use Hemafer for iron supplementation, but they should first consult a healthcare professional to confirm the need and appropriate dose.

Common side effects include nausea, constipation or loose stools, darkened stools, metallic taste, and abdominal cramping.

Discontinue if a severe allergic reaction occurs, signs of iron overload develop, or if the prescribing clinician advises stopping after laboratory monitoring.

Yes, iron can reduce the absorption of tetracyclines and fluoroquinolones; these antibiotics should be taken at least two hours apart from iron.

Hemafer may be used in children at appropriate doses, but dosing should be determined by a healthcare professional and kept out of reach of unsupervised children.

Hemoglobin, hematocrit, serum ferritin, and transferrin saturation are commonly measured to assess iron status during supplementation.

Iron overload is rare with appropriate dosing, but it can occur in individuals with hereditary hemochromatosis or when taken in excess; monitoring is recommended.

Vitamin C can enhance iron absorption, but taking large amounts may increase gastrointestinal irritation; moderate amounts are generally safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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