Hemorapyd (Cinchocaine Hydrochloride, Policresulen)

Hemorapyd is indicated for the symptomatic management of several anorectal conditions where local anesthesia and hemostasis are beneficial.

• Relief of pain and discomfort associated with hemorrhoids.
• Treatment of minor anal fissures to reduce spasm and bleeding.
• Management of rectal bleeding of non‑infectious origin.
• Adjunctive care after minor anorectal procedures.
• Support of tissue regeneration in mild rectal irritation.

Side effects of Hemorapyd are generally mild and related to its local action, but rare serious reactions may occur.

Common

• Mild burning or stinging at the application site.
• Transient numbness or tingling in the rectal area.
• Itching or mild irritation.
• Temporary redness or mild swelling.
• Slight discomfort during application.

Serious

• Allergic reaction such as rash, swelling, or hives.
• Severe burning or ulceration of the mucosa.
• Persistent numbness lasting beyond 24 hours.
• Signs of systemic toxicity (e.g., dizziness, tinnitus).
• Severe local infection.

When using Hemorapyd, consider the following precautions to minimize risks and ensure appropriate use.

• Do not apply to broken skin, open wounds, or infected areas without medical advice.
• Avoid use in patients with known hypersensitivity to cinchocaine, policresulen, or related compounds.
• Use cautiously in individuals taking anticoagulant or antiplatelet therapy due to potential increased bleeding.
• Pregnant or breastfeeding women should consult a healthcare professional before use.
• Keep the product out of reach of children and store at room temperature away from moisture.
• Discontinue use and seek medical attention if severe irritation or allergic symptoms develop.

Hemorapyd may interact with other medications or substances applied to the same area or absorbed systemically.

Avoid

• Concurrent use of other topical anesthetics containing lidocaine or similar agents, which may increase systemic exposure.
• Application together with potent vasoconstrictors that could impair local blood flow.

Use with caution

• Anticoagulants or antiplatelet drugs, as they may affect bleeding control.
• Systemic medications that lower seizure threshold, given the potential for local anesthetic absorption.
• Herbal or over‑the‑counter rectal preparations, which could alter mucosal integrity.