Product image of Hemosol B0 (Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate) supplied by GNH India

Hemosol B0

Active Ingredient:
Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate
Origin:
EU

Hemosol B0 (Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate)

Calcium, Lactic Acid, Magnesium, Sodium, Chloride Ion, Hydrogen Carbonate, the active ingredient in Hemosol B0, is an electrolyte solution presented as a solution for injection for haemodialysis and intravenous use. It corrects electrolyte and acid‑base imbalances during haemodialysis and provides fluid replacement in patients requiring intravenous therapy.

GNH India supplies Hemosol B0 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and dialysis clinics worldwide.

Manufacturer / TM Owner

Vantive Belgium

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Indications & Clinical Uses

Hemosol B0, an electrolyte solution used in renal replacement therapy, is indicated for:

  • Hemodialysis: restores electrolyte balance and corrects acid‑base disturbances during treatment.
  • Intravenous fluid replacement: provides essential electrolytes and volume support in patients with fluid loss.
  • Electrolyte balance correction: corrects deficiencies of calcium, magnesium, sodium, chloride and bicarbonate in various clinical settings.

How It Works

  • Hemosol B0 contains calcium, magnesium, sodium, chloride, bicarbonate and lactic acid which dissociate after infusion, contributing to the extracellular fluid electrolyte composition and buffering capacity. The ions support cardiac, neuromuscular and enzymatic functions, while bicarbonate and lactate help maintain physiological pH, thereby correcting acid‑base disturbances during haemodialysis or intravenous therapy.

Side Effects

Common Side Effects

  • Mild hypercalcemia: transient elevation of serum calcium.
  • Transient hypotension: slight drop in blood pressure during infusion.
  • Local irritation at infusion site: redness or discomfort.
  • Nausea: occasional feeling of queasiness.
  • Headache: mild to moderate.

Serious or Rare Side Effects

  • Severe hypermagnesemia: high magnesium levels causing cardiac effects.
  • Metabolic alkalosis: excessive bicarbonate leading to elevated pH.
  • Anaphylactic reaction: rare severe allergic response.
  • Electrolyte overload: risk of arrhythmia due to excess ions.

Precautions & Warnings

Before initiating therapy, evaluate the patient’s baseline electrolyte and acid‑base status.

  • Assess electrolyte levels: check serum calcium, magnesium, sodium and bicarbonate.
  • Monitor during infusion: frequent laboratory checks to avoid overload.
  • Adjust rate in cardiac disease: slower infusion for patients with heart failure.
  • Use caution in renal impairment: reduced clearance may increase risk.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Major Interactions (Avoid)

  • Calcium‑containing antacids: may cause hypercalcemia.
  • Magnesium sulfate infusion: risk of hypermagnesemia.
  • Sodium bicarbonate infusion: may lead to electrolyte overload.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: can alter electrolyte balance.
  • ACE inhibitors: may affect potassium and overall electrolyte status.
  • Blood transfusions: can influence calcium levels.

Frequently Asked Questions

Hemosol B0 is an electrolyte solution used primarily during haemodialysis and as an intravenous fluid replacement. It helps correct electrolyte imbalances, supports acid‑base regulation, and provides necessary ions such as calcium, magnesium, sodium, chloride and bicarbonate to patients undergoing renal replacement therapy or those needing rapid fluid and electrolyte repletion.

The solution delivers calcium, magnesium, sodium, chloride, bicarbonate and lactic acid directly into the bloodstream or dialysis circuit. These ions dissolve and integrate into the extracellular fluid, restoring normal electrolyte concentrations and buffering capacity. Bicarbonate and lactate act as pH buffers, while calcium and magnesium support cardiac and neuromuscular function, collectively correcting the disturbances seen in dialysis or fluid loss.

Dosing of Hemosol B0 is individualized. The prescribing clinician determines the volume and rate based on the patient’s current electrolyte profile, fluid status, and the specific requirements of the dialysis session or intravenous therapy. No fixed regimen is provided; dosage is adjusted to achieve target laboratory values and clinical goals.

Safety data for Hemosol B0 in pregnancy and lactation are limited. Because it contains essential electrolytes, it may be used when the potential benefit outweighs any theoretical risk, but the decision must be made by the treating physician after careful consideration of maternal and fetal health.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with standard bicarbonate‑based dialysis fluids, Hemosol B0 adds calcium, magnesium and lactate, offering a more comprehensive electrolyte profile. This can reduce the need for supplemental infusions during treatment. However, the choice depends on the patient’s individual electrolyte needs, the dialysis protocol and institutional preferences.

Hemosol B0 should be stored at ambient temperature, preferably below 25 °C. Keep the container sealed, protect it from direct sunlight, moisture and extreme temperature fluctuations. Do not freeze the solution, and inspect the vial for any particulate matter before use.

The solution is administered either as part of the haemodialysis circuit, where it mixes with the dialysate, or as an intravenous infusion through a calibrated infusion set. Administration rate is set by the clinician according to the patient’s electrolyte targets and overall fluid balance.

Serious risks include severe hypermagnesemia, metabolic alkalosis, anaphylactic reactions and electrolyte overload that can precipitate cardiac arrhythmias. Continuous monitoring of serum electrolytes and acid‑base status during therapy helps detect these complications early.

Patients with known hypersensitivity to any component of the solution should avoid it. Caution is also advised for individuals with uncontrolled cardiac disease, severe renal impairment not on dialysis, or those already receiving high‑dose electrolyte supplements that could lead to overload.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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