Heparin Gilvasan (Heparin Sodium)

Heparin Gilvasan is indicated for several clinical situations where anticoagulation is required.

• Prevention and treatment of deep vein thrombosis (DVT)
• Prophylaxis of pulmonary embolism (PE) in at‑risk patients
• Anticoagulation during cardiac surgery, including cardiopulmonary bypass
• Management of acute coronary syndromes (unstable angina, NSTEMI)
• Thromboprophylaxis in major orthopedic procedures such as hip or knee replacement

Side effects of Heparin Gilvasan vary in frequency and severity.

Common

• Minor bleeding or bruising at the injection site
• Small drops in platelet count (thrombocytopenia)
• Nausea or mild headache
• Elevated liver enzymes observed in laboratory tests
• Localized pain or irritation

Serious

• Major hemorrhage, including intracranial or gastrointestinal bleeding
• Heparin‑induced thrombocytopenia (HIT) with risk of thrombosis
• Spinal or epidural hematoma following neuraxial procedures
• Severe allergic reaction or anaphylaxis
• Adrenal or retroperitoneal hemorrhage

Before initiating Heparin Gilvasan, clinicians should evaluate several safety factors.

• Assess patient’s baseline bleeding risk and recent surgery history
• Monitor platelet counts regularly to detect HIT early
• Adjust dosing in patients with renal or hepatic impairment
• Avoid use in active major bleeding or uncontrolled hypertension
• Use with caution during pregnancy (Category B) and lactation
• Consider age, body weight, and concomitant antiplatelet therapy when dosing

Heparin Gilvasan may interact with other medications that affect hemostasis or platelet function.

Avoid

• Other systemic anticoagulants (e.g., warfarin, direct oral anticoagulants)
• Antiplatelet agents such as aspirin, clopidogrel, or ticagrelor
• Thrombolytic drugs (e.g., alteplase, streptokinase)
• Non‑steroidal anti‑inflammatory drugs (NSAIDs) that increase bleeding risk

Use with caution

• Certain antibiotics (e.g., ceftriaxone) that can potentiate anticoagulant effect
• ACE inhibitors and corticosteroids, which may affect blood pressure and clotting
• Herbal supplements like ginkgo biloba, garlic, or ginger that have antiplatelet properties
• High‑dose vitamin K preparations, which may interfere with coagulation monitoring