Herbion (Dry Extract Of Hederae Folium (5-7.5:1), Extraction Solvent: Ethanol 30% (M/M))

Herbion is indicated for symptomatic relief of common respiratory conditions where mucus accumulation impairs breathing.

• Acute cough associated with upper respiratory tract infections, especially when the cough is productive and mucus is difficult to clear.
• Chronic bronchitis characterized by a persistent, productive cough and increased bronchial secretions.
• Bronchial congestion due to mild to moderate respiratory tract infections, where enhanced secretion aids clearance.
• Post‑viral cough that continues after the acute phase, helping to mobilize residual mucus.
• Supportive therapy for individuals experiencing difficulty expectorating mucus, complementing other non‑prescription measures.

• Dry extract of Hederae folium contains saponins, flavonoids and mucilage that stimulate bronchial secretions and increase ciliary beat frequency. The saponins act as surfactants, reducing mucus viscosity, while flavonoids exert mild anti‑inflammatory effects that facilitate airway patency. Together these actions enhance mucociliary clearance, making it easier to expectorate accumulated secretions from the lower respiratory tract. Additionally, the mucilage component provides a soothing coating on the respiratory mucosa.

Herbion is generally well tolerated, but some users may experience mild to moderate adverse reactions.

Common

• Gastrointestinal discomfort such as nausea, abdominal cramps, or loose stools, typically transient.
• Unpleasant taste or a bitter after‑taste that may persist for a short period after ingestion.
• Mild oral or skin irritation, including erythema or a transient rash in the mouth or on the lips.
• Drowsiness, mild fatigue, or a feeling of slight somnolence, especially when taken in higher doses.

Serious

• Allergic reactions ranging from urticaria and angioedema to rare cases of anaphylactic shock, requiring immediate medical attention.
• Severe bronchospasm or worsening of asthma symptoms in individuals with known hypersensitivity to ivy extracts.
• Rare reports of hepatic enzyme elevation or liver function abnormalities, monitored in prolonged use.

Before using Herbion, consider the following precautions to ensure safe and appropriate use.

• Avoid use if you have a known allergy to ivy (Hedera) or any ingredient.
• Use with caution in asthma, COPD, or other reactive airway conditions.
• Pregnant or breastfeeding women should seek medical advice before use.
• Do not exceed the recommended short‑term duration; prolonged use may raise adverse‑event risk.
• Discuss concurrent use with other expectorants or mucolytics with a healthcare professional.
• Stop the product and obtain medical attention if any allergic reaction occurs.

Herbion may interact with certain medicines or substances; consider the following guidance.

Avoid

• Concurrent use with monoamine oxidase inhibitors (MAOIs) or other potent expectorants, which may cause excessive bronchial secretion.
• Combining with antihistamines that depress cough reflex, potentially reducing the therapeutic benefit.
• Use with herbal products containing similar ivy extracts, leading to additive effects and higher risk of side effects.

Use with caution

• Co‑administration with bronchodilators or corticosteroids; monitor for changes in airway responsiveness.
• Taking alongside drugs metabolized by the liver enzyme CYP450 isoforms that may be modestly affected by ivy constituents.
• Use with caution in patients on anticoagulant therapy, as rare reports suggest possible platelet function modulation.