Product image of Herbion (Dry Extract Of Hederae Folium (5-7.5:1), Extraction Solvent: Ethanol 30% (M/M)) supplied by GNH India

Herbion

Active Ingredient:
Dry Extract Of Hederae Folium (5-7.5:1), Extraction Solvent: Ethanol 30% (M/M)
Origin:
EU

Herbion (Dry Extract Of Hederae Folium (5-7.5:1), Extraction Solvent: Ethanol 30% (M/M))

Herbion is an over‑the‑counter oral product that contains a dry extract of Hederae folium (ivy leaf) prepared at a 5‑7.5:1 ratio with 30 % ethanol as the extraction solvent. The extract is supplied as a dry leaf extract without a specified strength and is marketed in the European Union as an expectorant for respiratory support.

Manufacturer / TM Owner

Krka, D.D., Novo Mesto

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Indications & Clinical Uses

Herbion is used to help relieve symptoms of common respiratory conditions where mucus accumulation impairs breathing. It is typically considered when a patient needs support for natural clearance of airway secretions.

  • Relief of productive cough associated with acute bronchitis.
  • Adjunct therapy for upper respiratory tract infections.
  • Management of chronic bronchitis symptoms.
  • Supportive care for mucus‑related cough in children over the age recommended by local regulations.
  • Use during seasonal colds to facilitate expectoration.

Side Effects

Side effects reported with ivy leaf extract are generally mild, but users should be aware of both common and less frequent reactions.

Common

  • Mild gastrointestinal discomfort such as nausea or stomach upset.
  • Transient taste alteration or a bitter after‑taste.
  • Mild skin irritation or rash at the oral mucosa.
  • Dizziness or light‑headedness, especially when standing quickly.

Serious

  • Allergic reactions including swelling of the face, lips, or throat.
  • Severe skin rash or hives (urticaria).
  • Bronchospasm or difficulty breathing in highly sensitive individuals.
  • Hepatic enzyme elevation reported in isolated cases.
  • Persistent vomiting or diarrhea leading to dehydration.

Precautions & Warnings

Before using Herbion, consider the following safety points to minimize risk.

  • Verify that the product is appropriate for the age group indicated on the label.
  • Avoid use in individuals with known hypersensitivity to ivy (Hedera) or any component of the formulation.
  • Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding.
  • Use caution in patients with chronic liver disease or severe gastrointestinal disorders.
  • Discontinue use and seek medical advice if any signs of an allergic reaction appear.
  • Do not exceed the recommended daily dose indicated on the packaging.

Avoid Interactions

Herbion may interact with certain medicines; awareness helps prevent adverse effects.

Avoid

  • Concurrent use with other strong expectorants or mucolytics without professional guidance.
  • Combining with monoamine oxidase inhibitors (MAOIs) due to limited safety data.

Use with caution

  • Antihistamines or bronchodilators, as additive effects on airway tone may occur.
  • Anticoagulant therapy (e.g., warfarin) because herbal extracts can influence bleeding risk.
  • Herbal supplements that also contain ivy or similar expectorant compounds.
  • Medications metabolized by the liver enzymes CYP450, pending further evidence.

Frequently Asked Questions

Herbion contains a dry extract of Hederae folium (ivy leaf) prepared at a 5‑7.5:1 ratio using 30 % ethanol as the extraction solvent. The process concentrates the leaf’s active compounds while removing excess water.

Herbion is commonly used to support the clearance of mucus in productive cough, acute and chronic bronchitis, and upper respiratory tract infections such as the common cold.

Ivy leaf extract stimulates bronchial secretions and enhances mucociliary clearance, which helps loosen and move mucus toward the throat, making expectoration easier.

Herbion may be used in children only if the product label specifies an appropriate age range and dosage. Always follow local regulations and consult a pediatrician before giving it to a child.

There is insufficient data on the safety of ivy leaf extract during pregnancy or lactation. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with a healthcare professional.

Common side effects include mild gastrointestinal discomfort, a bitter taste, transient dizziness, and occasional mild skin irritation in the mouth.

Serious reactions such as swelling of the face or throat, hives, bronchospasm, severe rash, or persistent vomiting require immediate discontinuation and medical evaluation.

Avoid combining Herbion with other strong expectorants or mucolytics without professional advice, and avoid use together with MAO inhibitors due to limited safety information.

Using other supplements that contain ivy leaf or similar expectorant herbs may increase the risk of side effects and should be avoided unless directed by a healthcare provider.

Herbion is intended for short‑term relief of acute symptoms. If cough persists beyond the recommended period on the label, seek medical advice to rule out underlying conditions.

Herbion is classified as an over‑the‑counter (OTC) medicinal product in the EU and is sold without a prescription for the indicated respiratory uses.

Product quality information, including manufacturing standards and batch testing, is typically provided by the marketing authorisation holder and can be accessed through the national medicines agency or the product’s official documentation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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