Hexaspray (Biclotymol)

Hexaspray is indicated for the symptomatic relief of several common oral conditions where a topical antiseptic effect is desired.

• Minor oral mucosal infections such as aphthous ulcers.
• Sore throat caused by bacterial or viral irritation.
• Early‑stage gingivitis or gum inflammation.
• Post‑dental‑procedure discomfort.
• General oral hygiene support in cases of halitosis.

• Biclotymol exerts its antiseptic activity by integrating into microbial cell membranes, disrupting lipid bilayer integrity. This leads to increased membrane permeability, loss of essential intracellular constituents, and ultimately bacterial or fungal cell death. The action is primarily local, with minimal systemic absorption, allowing effective reduction of microbial load on the oral mucosa.

Adverse reactions to Hexaspray are generally uncommon, but they may occur locally at the site of application.

Common

• Transient burning or stinging sensation.
• Mild oral irritation or dryness.
• Temporary alteration of taste.

Serious

• Allergic contact dermatitis of the oral mucosa.
• Severe swelling of the lips, tongue, or throat.
• Persistent ulceration or erosions.

Before using Hexaspray, consider the following precautions to ensure safe and appropriate use.

• Do not use if you have a known hypersensitivity to biclotymol or any spray excipients.
• Avoid application to extensive open wounds or large ulcerated areas in the mouth.
• Keep the product out of reach of children; accidental ingestion may cause gastrointestinal discomfort.
• Discontinue use and seek medical advice if irritation persists beyond 48 hours.
• Use with caution in patients with chronic oral mucosal disorders such as lichen planus.
• Do not combine with other oral antiseptic products without professional guidance.

Hexaspray may interact with other substances applied to the oral cavity; consider the following guidance.

Avoid

• Concurrent use of other topical oral antiseptics containing chlorhexidine or povidone‑iodine, which may reduce efficacy.
• Simultaneous application of oral corticosteroid sprays, as they can alter mucosal absorption.

Use with caution

• Alcohol‑based mouthwashes, which may increase local irritation.
• Systemic antibiotics, when used for the same infection, to avoid overlapping antimicrobial coverage.
• Herbal or homeopathic oral rinses, which could cause unpredictable local reactions.